Sulconazole Nitrate - 10mM in DMSO , CAS No.61318-91-0

CAS: 61318-91-0 Cat. No.: S408216 Formula: C₁₈H₁₅Cl₃N₂S·HNO₃ Peso molecolare: 460.76 Numero EC: 624-696-6 PubChem CID: 65495

GRADE & PURITY 10mM in DMSO

Synonyms

1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (9CI)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Sulconazole Nitrate Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
In vitro

Sulconazole Nitrate possesses a broad spectrum of activity in vitro against dermatophytes, yeasts and some Gram-positive bacteria at concentrations below 5 mg/L in vitro. It has been shown that against representatives of pathogenic yeasts, dermatophytes and Aspergilli, the RIF values of sulconazole are broadly similar to those of other imidazoles. The fungicidal potency of sulconazole in vitro depends on its concentration and on the growth phase of the inoculum cells. Sulconazole has also demonstrated antibacterial activity in vitro, with MIC values below 12.5 mg/L.

In vivo

The efficacy and safety of sulconazole 1% cream has been demonstrated in controlled clinical studies in patients with superficial dermatophyte or yeast infections. To minimise the risk of reinfection treatment should continue for 3 weeks in Candida infections, tinea cruris, tinea corporis and pityriasis versicolor, and for 4 weeks in patients with tinea pedis.
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥95%

Specifications

Sinonimi

1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (9CI)

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Tipo di azione

INHIBITOR

Nomi e identificatori

Isomeri SMILES

C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

WGK Germania

3

RTECS

NI4475000

PubChem CID

65495

Peso molecolare

460.76

Obiettivi associati (umani)

HSP90AA1 Tchem Heat shock protein HSP 90-alpha (1 Activities)

Discover Target: HSP90AA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 100 mg/mL (153.61 mM); Water: Insoluble; Ethanol: Insoluble
• Punto di fusione (°C): 152 °C