Sulfopin - Moligand™, 10mM in DMSO , Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1, CAS No.2451481-08-4, Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

CAS: 2451481-08-4 Cat. No.: S580530 Formula: C₁₁H₂₀ClNO₃S Peso molecolare: 281.8 Numero EC: 873-703-0 PubChem CID: 155804394

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide | HY-139361 | Z3375875148 | 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda6-thiolan-3-yl)acetamide | EN300-6495949 | 2451481-08-4 | AKOS040759747 | PIN1-3 | GTPL11540 | sulfopin | SC

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Product description：

Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.

Specifications

Sinonimi

2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide | HY-139361 | Z3375875148 | 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda6-thiolan-3-yl)acetamide | EN300-6495949 | 2451481-08-4 | AKOS040759747 | PIN1-3 | GTPL11540 | sulfopin | SC

Specifiche e purezza

Moligand™, 10mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Meccanismo d'azione

Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

Nomi e identificatori

• Sorrisi canonici: CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl
• IUPAC Name: 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide
• InChIKey: NMHVAHHYKGXBMY-UHFFFAOYSA-N
• INCHI: 1S/C11H20ClNO3S/c1-11(2,3)8-13(10(14)6-12)9-4-5-17(15,16)7-9/h9H,4-8H2,1-3H3
• Isomeri SMILES: CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl
• CAS alternativo: 2451481-08-4
• PubChem CID: 155804394
• Peso molecolare: 281.8

Obiettivi associati (umani)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (0 Activities)

Discover Target: PIN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Peso molecolare: 281.800 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 281.085 Da
• Monoisotopic Mass: 281.085 Da
• Topological Polar Surface Area: 62.800 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 381.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1