Taraxerol - Moligand™, ≥98% , CAS No.127-22-0

CAS: 127-22-0 Cat. No.: T651169 Formula: C₃₀H₅₀O Peso molecolare: 426.72 PubChem CID: 92097

GRADE & PURITY Moligand™, ≥98%

Synonyms

alnulin | TARAXEROL [MI] | DTXSID001026552 | 27-Norolean-14-en-3-ol, 13-methyl-, (3beta,13alpha)- | skimmiol | BDBM50242128 | ISOOLEAN-14-EN-3beta-OL | AKOS032962064 | ISOOLEAN-14-EN-3.BETA.-OL | SCHEMBL569463 | NIOSH/AM5850000 | (3beta)-D-friedoolean-14-

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Panoramica

Taraxerol is isolated from Taraxacum mongolicum , and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis.

Specifications

Sinonimi

alnulin | TARAXEROL [MI] | DTXSID001026552 | 27-Norolean-14-en-3-ol, 13-methyl-, (3beta,13alpha)- | skimmiol | BDBM50242128 | ISOOLEAN-14-EN-3beta-OL | AKOS032962064 | ISOOLEAN-14-EN-3.BETA.-OL | SCHEMBL569463 | NIOSH/AM5850000 | (3beta)-D-friedoolean-14-

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Taraxerol is isolated from Taraxacum mongolicum , and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis.

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: CC1(CCC2(CC=C3C4(CCC5C(C(CCC5(C4CCC3(C2C1)C)C)O)(C)C)C)C)C
• IUPAC Name: (3S,4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,8,9,10,12,12a,13,14,14a-tetradecahydropicen-3-ol
• InChIKey: GGGUGZHBAOMSFJ-GADYQYKKSA-N
• INCHI: 1S/C30H50O/c1-25(2)17-18-27(5)13-9-21-29(7)14-10-20-26(3,4)24(31)12-16-28(20,6)22(29)11-15-30(21,8)23(27)19-25/h9,20,22-24,31H,10-19H2,1-8H3/t20-,22+,23+,24-,27-,28-,29-,30+/m0/s1
• Isomeri SMILES: C[C@]12CCC(C[C@H]1[C@@]3(CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4(C3=CC2)C)(C)C)O)C)C)(C)C
• CAS alternativo: 127-22-0
• PubChem CID: 92097
• Termini MeSH: 3beta-taraxerol;D-friedoolean-14-en-3 beta-ol;taraxerol
• Peso molecolare: 426.72

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Prenol lipids
      • Subclass Sesterterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Prenol lipids
• Subclass: Sesterterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Scalarane sesterterpenoids
• Alternative Parents: Secondary alcohols Cyclic alcohols and derivatives Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Scalarane sesterterpenoid - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as scalarane sesterterpenoids. These are sesterterpenoids with a structure based on the scalarane backbone. Scalarane is a tetracyclic compound, which is similar the homoandrostane with five methyl groups at the 4-, 4-, 8-, 17-, 17a-positions.
• External Descriptors: Taraxerane, multiflorane, glutinane and friedelane triterpenoids - Dammarenes

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: THF : 10 mg/mL (23.43 mM; Need ultrasonic) DMSO : <1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble or slightly soluble) H2O : <0.1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble)
• Sensibilità: Light sensitive
• Peso molecolare: 426.700 g/mol
• XLogP3: 9.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 426.386 Da
• Monoisotopic Mass: 426.386 Da
• Topological Polar Surface Area: 20.200 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 790.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1