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FLT1

DescrizioneVascular endothelial growth factor receptor 1

Gene and Protein Information

Gene ID2321
Uniprot Accession IDs P17948 A3E342 A3E344 A8KA71 B0LPF1 B2BF46 B2BF47 B2BF48 B3FR89 B5A923 F5H5L6 O60722 P16057 Q12954 VEGFR-1
Ensembl ID ENSP00000282397
Symbol FLT FRT VEGFR1 FLT FLT-1 VEGFR1 VEGFR-1
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMASTLVVADSRISGIYICIASNKVGTVGRNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFIRKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSVTSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNSVVLYSTPPI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeCodice fiscaleOther Gene IDSorgenti
Chimp452512FLT1fms related tyrosine kinase 19598VGNC:7287OMA, EggNOG
Macaque574133FLT1fms related tyrosine kinase 19544Inparanoid, OMA, EggNOG
Mouse14254Flt1FMS-like tyrosine kinase 110090MGI:95558Inparanoid, OMA, EggNOG
Rat54251Flt1FMS-related tyrosine kinase 110116RGD:2621Inparanoid, OMA, EggNOG
Dog403727FLT1fms related tyrosine kinase 19615VGNC:40907Inparanoid, OMA, EggNOG
Horse100033957FLT1fms related tyrosine kinase 19796VGNC:18067Inparanoid, OMA, EggNOG
Cow503620FLT1fms related tyrosine kinase 19913VGNC:29041Inparanoid, OMA, EggNOG
Pig396763FLT1fms related tyrosine kinase 19823OMA, EggNOG
Opossum100025304FLT1fms related tyrosine kinase 113616Inparanoid, OMA, EggNOG
PlatypusFLT1fms related tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763]9258OMA, EggNOG
Chicken374100FLT1fms related tyrosine kinase 19031CGNC:49041Inparanoid, OMA
Anole lizard100556703flt1fms related tyrosine kinase 128377Inparanoid, OMA, EggNOG
Zebrafish544667flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)7955ZDB-GENE-050407-1Inparanoid, OMA, EggNOG
Fruitfly34127PvrPDGF- and VEGF-receptor related7227FBgn0032006Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    VEGFR family    /    Vascular endothelial growth factor receptor 1

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilitàVedi dettagli

Associated Antibodies

NomeSpecificationsSpecies reactivityApplicazioneDisponibilitàVedi dettagli

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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