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TRPM2

DescrizioneTransient receptor potential cation channel subfamily M member 2

Gene and Protein Information

Gene ID7226
Uniprot Accession IDs O94759 D3DSL6 Q5KTC2 Q6J3P5 Q96KN6 Q96Q93
Ensembl ID ENSP00000381023
Symbol EREG1 KNP3 LTRPC2 TRPC7 KNP3 EREG1 TRPC7 LTRPC2 NUDT9H LTrpC-2 NUDT9L1
FamilyBelongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
Sequence
MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSWRLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTAQALHWIVRTLRASGFSSEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFGAHY
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeCodice fiscaleOther Gene IDSorgenti
Chimp470101TRPM2transient receptor potential cation channel subfamily M member 29598VGNC:7467OMA, EggNOG
Macaque722161TRPM2transient receptor potential cation channel subfamily M member 29544OMA, EggNOG
Mouse28240Trpm2transient receptor potential cation channel, subfamily M, member 210090MGI:1351901Inparanoid, OMA, EggNOG
Rat294329Trpm2transient receptor potential cation channel, subfamily M, member 210116RGD:1311889Inparanoid, OMA, EggNOG
Dog100855763LOC100855763transient receptor potential cation channel subfamily M member 29615Inparanoid, OMA, EggNOG
Horse100056810TRPM2transient receptor potential cation channel subfamily M member 29796VGNC:24557Inparanoid, OMA, EggNOG
Cow508029TRPM2transient receptor potential cation channel subfamily M member 29913VGNC:36389Inparanoid, OMA, EggNOG
Pig100622032TRPM2transient receptor potential cation channel subfamily M member 29823OMA, EggNOG
Chicken424835TRPM2transient receptor potential cation channel subfamily M member 29031CGNC:4193Inparanoid, OMA, EggNOG
Anole lizard100556895trpm2transient receptor potential cation channel subfamily M member 228377Inparanoid, OMA, EggNOG
Zebrafish799412trpm2transient receptor potential cation channel, subfamily M, member 27955ZDB-GENE-061214-4Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ion channel    /    Transient receptor potential cation channel subfamily m member 2
protein    /    transporter    /    receptor    /    Transient receptor potential cation channel subfamily m member 2
DTO Classes
protein    /    Ion channel    /    Transient receptor potential calcium channel (TRP-CC) family    /    LTrpC subfamily    /    TRPM2 sub-subfamily    /    Transient receptor potential cation channel subfamily m member 2

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilitàVedi dettagli

Associated Antibodies

NomeSpecificheSpecies reactivityApplicazioneDisponibilitàVedi dettagli

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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