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| Descrizione | Receptor tyrosine-protein kinase erbB-4 |
|---|
Gene and Protein Information
| Gene ID | 2066 |
|---|---|
| Uniprot Accession IDs | Q15303 B7ZLD7 B7ZLE2 B7ZLE3 Q2M1W1 Q59EW4 |
| Ensembl ID | ENSP00000342235 |
| Symbol | HER4 HER4 ALS19 p180erbB4 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
| Sequence | MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV Mostra altro |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nome | Codice fiscale | Other Gene ID | Sorgenti |
|---|---|---|---|---|---|---|
| Chimp | 459919 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9598 | VGNC:372 | OMA, EggNOG |
| Macaque | 693341 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9544 | OMA, EggNOG | |
| Mouse | 13869 | Erbb4 | erb-b2 receptor tyrosine kinase 4 | 10090 | MGI:104771 | Inparanoid, OMA, EggNOG |
| Rat | 59323 | Erbb4 | erb-b2 receptor tyrosine kinase 4 | 10116 | RGD:620486 | Inparanoid, OMA, EggNOG |
| Dog | 488508 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9615 | VGNC:40437 | Inparanoid, OMA, EggNOG |
| Horse | 100050182 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9796 | VGNC:17651 | Inparanoid, OMA, EggNOG |
| Opossum | 100014865 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100077353 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 395671 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9031 | CGNC:49428 | Inparanoid, OMA |
| Anole lizard | 100558986 | erbb4 | erb-b2 receptor tyrosine kinase 4 | 28377 | Inparanoid, OMA | |
| Xenopus | 100493234 | erbb4 | erb-b2 receptor tyrosine kinase 4 | 8364 | XB-GENE-877077 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / EGFR family / Receptor tyrosine-protein kinase erbb-4
protein / Kinase / Protein kinase / TK group / EGFR family / Receptor tyrosine-protein kinase erbb-4
Associated Recombinant Proteins
| Nome | Specification and purity | Expression system | Protein label | Disponibilità | Vedi dettagli |
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Associated Antibodies
| Nome | Specifications | Species reactivity | Applicazione | Disponibilità | Vedi dettagli |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nome | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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