Tauroursodeoxycholate dihydrate - Moligand™, 10 mM in DMSO , CAS No.117609-50-4

CAS: 117609-50-4 Cat. No.: T1498916 Formula: C₂₆H₄₉NO₈S Peso molecolare: 535.7 PubChem CID: 71306862

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12 . Tauroursodeoxycholate also inhibits ERK .

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.O.O
• CAS alternativo: 14605-22-2
• PubChem CID: 71306862
• Peso molecolare: 535.7

Riferimenti

1. Xi Chen, Long-Yun Li, Jin-Lan Jiang, Kai Li, Zhen-Bo Su, Fu-Qiang Zhang, Wen-Jing Zhang, Guo-Qing Zhao.  (2018)  Propofol elicits autophagy via endoplasmic reticulum stress and calcium exchange in C2C12 myoblast cell line.  PLoS One,  13  (5): (e0197934).  [PMID:29795639] [10.1371/journal.pone.0197934]

2. Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu.  (2025)  Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer.  PHARMACOLOGICAL RESEARCH,      [PMID:39894186] [10.1016/j.phrs.2025.107636]

3. Yilong Liu, Ruoqi Wang, Jinren Zhou, Qiang Lyu, Xiaoyong Zhao, Xiaochun Yang, Kunsong Chen, Zhiwei Gao, Xian Li.  (2025)  Myricetin alleviates high-fat diet-induced atherosclerosis in ApoE−/− mice by regulating bile acid metabolism involved in gut microbiota remodeling.  Food & Function,      [PMID:40059779] [10.1039/D5FO00374A]

4. Wen Ma, Mingxia Liu, Mengling Tu, Gang Wang, Jun Li, Fen Liu, Jian Yang, Xianjiang Li.  (2024)  Novel multi-layered MXene as laser desorption ionization mass spectrometry matrix for rapid detection of small biomolecules.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.157466]

5. Guang Chen, Gang Yu, Zheng Yong, Hui Yan, Ruibin Su, Huijun Wang.  (2021)  A large dose of methamphetamine inhibits drug‑evoked synaptic plasticity via ER stress in the hippocampus.  Molecular Medicine Reports,  23  (4): (1-1).  [PMID:33576466] [10.3892/mmr.2021.11917]

6. Lin Xu, Yuanyuan Zhao, Yang Yang, Enbo Qi, Boao Liu, Peili Zhuang, Shiyi Song, Tingmin Chang, Zhiguo Chen, Xiaohong Kang, Xiwen Xiong.  (2025)  Constitutive hepatic mTORC1 activation aggravates alcohol-induced liver injury via endoplasmic reticulum stress-mediated ferroptosis.  AMERICAN JOURNAL OF PATHOLOGY,      [PMID:40204188] [10.1016/j.ajpath.2025.03.005]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 117609-50-4, the molecular formula is C26H49NO8S, and the molecular weight is 535.7 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.