Tegafur (FT-207) - Moligand™, 10mM in DMSO , DNA inhibitor, CAS No.17902-23-7, DNA inhibitor

CAS: 17902-23-7 Cat. No.: T407930 Formula: C₈H₉FN₂O₃ Peso molecolare: 200.17 Beilstein Registry Number: 24(5)6,285 Numero EC: 241-846-2 PubChem CID: 5386

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

NSC 148958 | 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Tegafur (FT-207) Tegafur (FT-207, NSC 148958) is a substance being used in the treatment of some types of cancer.
In vitro

In vivo

Cell Data

cell lines：GTL-16 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinonimi

NSC 148958 | 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Specifiche e purezza

Moligand™, 10mM in DMSO

Meccanismi biochimici e fisiologici

Tegafur (FT-207, NSC 148958) is a substance being used in the treatment of some types of cancer.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Meccanismo d'azione

DNA inhibitor

Proprietà del prodotto

• ALogP: -0.3

Nomi e identificatori

• Isomeri SMILES: C1CC(OC1)N2C=C(C(=O)NC2=O)F
• WGK Germania: 3
• RTECS: YR0450000
• CAS alternativo: 17902-23-7,82294-77-7
• PubChem CID: 5386
• Termini MeSH: 1-(2-Tetrahydrofuryl)-5-fluorouracil;1-(Tetrahydro-2-furanyl)-5-fluorouracil;5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione;Florafur;Fluorofur;FT 207;FT-207;FT207;Ftorafur;Futraful;N1-(2'-Tetrahydrofuryl)-5-fluorouracil;Sunfural S;Tegafur;Uftoral;U
• Peso molecolare: 200.17
• Beilstein: 24(5)6,285
• Reaxy-Rn: 525766

Proprietà chimiche e fisiche

• Punto di fusione (°C): 171-173°C

Riferimenti

1. Hanwen Liu, Ying Liu, Ting Zhou, Penghui Zhou, Jianguo Li, Anping Deng.  (2022)  Ultrasensitive and Specific Detection of Anticancer Drug 5-Fluorouracil in Blood Samples by a Surface-Enhanced Raman Scattering (SERS)-Based Lateral Flow Immunochromatographic Assay.  MOLECULES,  27  (13): (4019).  [PMID:35807264] [10.3390/molecules27134019]

2. Ting Zhou, Guangzhao He, Changjia Hu, Kang Wu, Ying Liu, Jianguo Li, Anping Deng.  (2022)  Development of a highly sensitive and specific monoclonal antibody-based ELISA coupled with immuno-affinity extraction for the detection of anticancer drug 5-fluorouracil in blood samples.  TALANTA,      [PMID:35696979] [10.1016/j.talanta.2022.123655]

3. Hong Shao, Wen Li, Zhuohan Li, Peng Shi, Zheng Li, Yuxiang Wang, Chao Pi, Lingmao Zhao, Wenwu Zheng, Yumeng Wei, Ling Zhao.  (2026)  Construction of in situ temperature-sensitive gel of Tegafur derivative TAK5399 and its evaluation against breast cancer.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:41592669] [10.1016/j.ejps.2026.107452]

4. Zhiqiang Zhang, Chenxi Fang, Yingjie Ma, Anning Li, Yunfeng Dai, Long Chen, Jungang Ren, Meitao Duan, Ming Chen, Li Wang, Chen Wang.  (2026)  A Doppler/Near-Infrared-Mediated Visual Real-Time Positioning Microbubble-Based Drug Delivery System Integrating Chemotherapy, Photodynamic Therapy, and Photothermal Therapy for the Treatment of Superficial Tumors.  MOLECULAR PHARMACEUTICS,      [PMID:41732842] [10.1021/acs.molpharmaceut.5c01844]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 17902-23-7, the molecular formula is C8H9FN2O3, and the molecular weight is 200.17 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.