Teicoplanin - Moligand™, 10mM in Water , CAS No.61036-62-2

CAS: 61036-62-2 Cat. No.: T425056 Formula: C₇₇H₇₇N₉O₃₁Cl₂·R Peso molecolare: 1900

GRADE & PURITY Moligand™, 10mM in Water

Synonyms

Teichomycin

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Teicoplanin is a semisynthetic glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.

Specifications

Sinonimi

Teichomycin

Specifiche e purezza

Moligand™, 10mM in Water

Meccanismi biochimici e fisiologici

Antibiotic. Active against Gram-positive bacteria. Able to inhibit cell wall biosynthesis.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Pubchem Sid: 528767473
• Sorrisi canonici: CCCCCCCCCC(=O)NC1C(C(C(OC1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)C(C6C(=O)NC(C7=C(C(=CC(=C7)O)OC8C(C(C(C(O8)CO)O)O)O)C9=C(C=CC(=C9)C(C(=O)N6)NC(=O)C4NC(=O)C1C2=CC(=CC(=C2)OC2=C(C=CC(=C2)C(C(=O)NC(CC2=CC(=C(O3)C=C2)Cl)C(=O)N1)N)O)O)O)C(=O)O)OC1C(C(C(C(O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• IUPAC Name: (1S,2R,19R,22S,34S,37R,40R,52R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-amino-5,15-dichloro-64-[(2S,3R,4R,5S,6R)-3-(decanoylamino)-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14,16,23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,62,65-henicosaene-52-carboxylic acid
• InChIKey: BJNLLBUOHPVGFT-VPMXZCLFSA-N
• INCHI: 1S/C88H97Cl2N9O33/c1-3-4-5-6-7-8-9-10-60(108)94-68-74(113)71(110)58(32-101)129-87(68)132-78-55-26-40-27-56(78)126-52-18-14-38(24-47(52)90)77(131-86-67(92-34(2)103)73(112)70(109)57(31-100)128-86)69-84(121)98-66(85(122)123)45-29-42(105)30-54(127-88-76(115)75(114)72(111)59(33-102)130-88)61(45)44-23-37(13-15-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-21-41(104)28-43(22-39)124-53-25-36(12-16-50(53)107)62(91)80(117)93-48(79(116)95-64)20-35-11-17-51(125-55)46(89)19-35/h11-19,21-30,48,57-59,62-77,86-88,100-102,104-107,109-115H,3-10,20,31-33,91H2,1-2H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/t48-,57-,58-,59-,62+,63-,64+,65-,66-,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1
• Isomeri SMILES: CCCCCCCCCC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)[C@H]([C@H]6C(=O)N[C@H](C7=C(C(=CC(=C7)O)O[C@@H]8[C@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C9=C(C=CC(=C9)[C@H](C(=O)N6)NC(=O)[C@@H]4NC(=O)[C@@H]1C2=CC(=CC(=C2)OC2=C(C=CC(=C2)[C@@H](C(=O)N[C@H](CC2=CC(=C(O3)C=C2)Cl)C(=O)N1)N)O)O)O)C(=O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• Peso molecolare: 1900
• Reaxy-Rn: 25078866
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25078866&ln=

Proprietà chimiche e fisiche

• Sensibilità: Heat sensitive
• Indice di rifrazione: 1.76

Riferimenti

1. Yechang Guo, Shaofeng Wang, Peiyue Li, Pan Zhang, Wei Wang.  (2023)  Rapid Colloidal Gold Immunoassay for Pharmacokinetic Evaluation of Vancomycin in the Cerebrospinal Fluid and Plasma of Beagle Dogs.  SENSORS,  23  (21): (8978).  [PMID:37960677] [10.3390/s23218978]

2. Lu Ye, Jiang Longlong, Yu Yang, Wang Dehua, Sun Wentao, Liu Yang, Yu Jing, Zhang Jun, Wang Kai, Hu Han, Wang Xiao, Ma Qingming, Wang Xiaoxiong.  (2022)  Liquid-liquid triboelectric nanogenerator based on the immiscible interface of an aqueous two-phase system.  Nature Communications,  13  (1): (1-12).  [PMID:36085155] [10.1038/s41467-022-33086-2]

3. Xianghai Zeng, Pengfei She, Linying Zhou, Shijia Li, Zubair Hussain, Lihua Chen, Yong Wu.  (2020)  Drug repurposing: Antimicrobial and antibiofilm effects of penfluridol against Enterococcus faecalis.  MicrobiologyOpen,  10  (1): (e1148).  [PMID:33345466] [10.1002/mbo3.1148]

4. Wenwen Cao, Anli Qin, Wenqian Zhu, Chaohai Pang, Zhongsheng Yi, Xionghui Ma, Shuhuai Li, Jianping Li.  (2024)  In Situ growth of high-crystallinity MOF@CTF core-shell hybrid heterostructures and their application in photoelectrochemical sensing of vancomycin.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2024.104963]

5. Liufu Zhang, Jianwei Di, Haoyang Wang, Zhiwei Zhou, Yuxi Wang, Jun Long, Yanqiu Zhang, Jing Guo, Xu Jiang, Lu Shao.  (2025)  Tear-film-inspired interfacial polymerization engineering nanofiltration membrane architecture for highly efficient antibiotic desalination.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.164990]

6. Chen Huang, Ling-Jie Guo, Jia-Yi Li, Yue-Wen Chen, Bing Wu, Yi-Wei Liu, Chen-Zhi Zhang, Wei-Wei Lin, Ye Yang, Jin-Yuan Chen, Zhou-Jie Liu.  (2025)  A CRISPR-Cas12a Fluorescent Aptasensor for Point-of-Care Drug Concentration Detection: A Synergistic Regulation by DNA Aptamer and RNA Blocker.  ANALYTICAL CHEMISTRY,      [PMID:41144643] [10.1021/acs.analchem.5c03744]

7. Luqin Lv, Yizhuo Zhang, Yaxin Fan, Beining Guo, Yijian Chen.  (2026)  Bivalent aptamer-assisted CRISPR-Cas12a sensor for precise vancomycin therapeutic drug monitoring.  TALANTA,      [PMID:] [10.1016/j.talanta.2026.130504]