Name: Telacebec (Q203) - ≥98% , CAS No.1334719-95-7
Brand: Aladdin Scientific
SKU: T413823
Availability: InStock

Telacebec (Q203) - ≥98% , CAS No.1334719-95-7

CAS: 1334719-95-7 Cat. No.: T413823 Formula: C₂₉H₂₈ClF₃N₄O₂ Peso molecolare: 557.01 Numero EC: 819-357-6 PubChem CID: 68234908

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Telacebec (Q203) - ≥98% CAS No(1334719-95-7) by Aladdin Scientific

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Disponibile su ordine

QUALITÀ & PUREZZA ≥98%

Synonyms

F3385-4658 | SCHEMBL12295312 | EN300-218150 | IAP6; Telacebec; Q203 | TELACEBEC [USAN] | HY-101040 | AC-36141 | UNII-55G92WGH3X | InChI=1/C8H10O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,9-11H,3-4H2 | D11263 | Telacebec (Q203) | 1334719-95-7 | AKOS037515678 | AS

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Scheda delle specifiche

Panoramica Specifiche Nomi e identificatori Documentazione Dati avanzati Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Calcolatori di soluzioni Recensioni

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Perché questa qualità

≥98% per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.

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Stoccaggio e spedizione

Store at -20°C Spedizione Ice chest + Ice pads. Consultare il COA specifico del lotto per le specifiche esatte.

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Documenti di qualità

SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.

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Prova documentale

Citato in 0 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.

Panoramica

Information

Telacebec (Q203, IAP6) is a novel antituberculosis drug that targetsMycobacterium tuberculosiscellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.

Specifiche

Sinonimi

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Telacebec (Q203, IAP6) is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

528767474

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528767474

Sorrisi canonici

CCC1=C(N2C=C(C=CC2=N1)Cl)C(=O)NCC3=CC=C(C=C3)N4CCC(CC4)C5=CC=C(C=C5)OC(F)(F)F

IUPAC Name

6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide

InChIKey

OJICYBSWSZGRFB-UHFFFAOYSA-N

INCHI

1S/C29H28ClF3N4O2/c1-2-25-27(37-18-22(30)7-12-26(37)35-25)28(38)34-17-19-3-8-23(9-4-19)36-15-13-21(14-16-36)20-5-10-24(11-6-20)39-29(31,32)33/h3-12,18,21H,2,13-17H2,1H3,(H,34,38)

Isomeri SMILES

CCC1=C(N2C=C(C=CC2=N1)Cl)C(=O)NCC3=CC=C(C=C3)N4CCC(CC4)C5=CC=C(C=C5)OC(F)(F)F

PubChem CID

68234908

Peso molecolare

557.01

Documentazione

📋 Scheda di dati di sicurezza (SDS)

Documento completo su pericoli, manipolazione, stoccaggio e conformità normativa.

<<<<<<< HEAD Scarica SDS → ======= Scarica SDS → >>>>>>> release248-p3

✅ Certificato di analisi (COA)

Dati di qualità specifici del lotto. Inserisci il numero di lotto per recuperare il COA esatto.

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📊 Scheda tecnica

Riepilogo di riferimento rapido delle specifiche e applicazioni del prodotto.

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🔬 Scheda delle specifiche

Attributi di qualità completi e criteri di accettazione per questa qualità.

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Dati avanzati

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Classe Piperidines
    - Subclass Phenylpiperidines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Classe	Piperidines
Subclass	Phenylpiperidines
Intermediate Tree Nodes	Not available
Direct Parent	Phenylpiperidines
Alternative Parents	Pyridinecarboxamides Imidazo[1,2-a]pyridines Imidazopyridines 2-heteroaryl carboxamides Aniline and substituted anilines Phenoxy compounds Phenol ethers Dialkylarylamines Aralkylamines Carbonylimidazoles Aryl chlorides N-substituted imidazoles Heteroaromatic compounds Trihalomethanes Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Hydrocarbon derivatives Organochlorides Organofluorides Organooxygen compounds Organic oxides Alkyl fluorides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Phenylpiperidine - Pyridinecarboxamide - Imidazo[1,2-a]pyridine - Imidazopyridine - 2-heteroaryl carboxamide - Phenoxy compound - Phenol ether - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Imidazole-4-carbonyl group - Aralkylamine - Aryl chloride - Aryl halide - Pyridine - Benzenoid - N-substituted imidazole - Monocyclic benzene moiety - Azole - Imidazole - Heteroaromatic compound - Amino acid or derivatives - Trihalomethane - Carboxamide group - Tertiary amine - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organohalogen compound - Alkyl fluoride - Hydrocarbon derivative - Amine - Halomethane - Alkyl halide - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Descrizione	This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK293 (82097 Activities)

Lot Number	Certificate Type	Data	Oggetto
B2428340	Certificate of Analysis	Jan 22, 2024	T413823
B2428341	Certificate of Analysis	Jan 22, 2024	T413823

Solubilità	Solubility (25°C) In vitro DMSO: 20 mg/mL (35.9 mM); Ethanol: 20 mg/mL (35.9 mM); Water: Insoluble;
Peso molecolare	557.000 g/mol
XLogP3	7.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	556.185 Da
Monoisotopic Mass	556.185 Da
Topological Polar Surface Area	58.900 Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	796.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1