Teniposide - Moligand™, 10mM in DMSO , DNA topoisomerase II inhibitor, CAS No.29767-20-2, DNA topoisomerase II inhibitor

CAS: 29767-20-2 Cat. No.: T408960 Formula: C₃₂H₃₂O₁₃S Peso molecolare: 656.65 Numero EC: 249-831-2 PubChem CID: 452548

QUALITÀ & PUREZZA Moligand™, 10mM in DMSO

Synonyms

NSC 122819, VM-26 | (5R,​5aR,​8aR,​9S)​-5,​8,​8a,​9-​tetrahydro-​5-​(4-​hydroxy-​3,​5-​dimethoxyphenyl)​-​9-​[[4,​6-​O-​[(R)​-​2-​thienylmethylene]​-​β-​D-​glucopyranosyl]​oxy]​-furo[3',​4':6,​7]​naphtho[2,​3-​d]​-​1,​3-​dioxol-​6(5aH)​-​one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).
In vitro

In vivo

Cell Data

cell lines：Fischer rat thyroid (FRT) cells

Concentrations：

Incubation Time：

Powder Purity:≥95%

Specifiche

Sinonimi

NSC 122819, VM-26 | (5R,​5aR,​8aR,​9S)​-5,​8,​8a,​9-​tetrahydro-​5-​(4-​hydroxy-​3,​5-​dimethoxyphenyl)​-​9-​[[4,​6-​O-​[(R)​-​2-​thienylmethylene]​-​β-​D-​glucopyranosyl]​oxy]​-furo[3',​4':6,​7]​naphtho[2,​3-​d]​-​1,​3-​dioxol-​6(5aH)​-​one

Specifiche e purezza

Moligand™, 10mM in DMSO

Meccanismi biochimici e fisiologici

Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Meccanismo d'azione

DNA topoisomerase II inhibitor

Proprietà del prodotto

ALogP

1.2

Nomi e identificatori

Isomeri SMILES

COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)CO[C@H](O7)C8=CC=CS8)O)O

PubChem CID

452548

Peso molecolare

656.65

Obiettivi associati (umani)

TOP2A Tclin DNA topoisomerase 2-alpha (0 Activities)

Discover Target: TOP2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 47 mg/mL (201.11 mM); Water: Insoluble; Ethanol: Insoluble
• Rotazione specifica [α]: -111° (C=1,CHCl3:MeOH=9:1)
• Punto di fusione (°C): 247 °C(dec.)