Tetrabutyl Orthosilicate - ≥98%(GC) , CAS No.4766-57-8

CAS: 4766-57-8 Cat. No.: T161830 Molecular Weight: 320.55 EC Number: 225-305-8 PubChem CID: 78500
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(GC)
Synonyms
NB6CXG7SPH | A872098 | EINECS 224-851-4 | MKC SILICATE BTS | Glycine, N-[(1,1-dimethylethoxy)carbonyl]- | SCHEMBL49555 | AKOS015833678 | Butyl silicate | Silane, tetrabutoxy- | Si(OCH2CH2CH2CH3)4 | Tetrabutoxysilane | Silicic acid (H4SiO4), tetrabutyl est
Storage
Room temperature,Argon charged,Cool
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5ml
T161830-5ml
1
$9.90
25ml
T161830-25ml
3
$17.90
100ml
T161830-100ml
3
$55.90
500ml
T161830-500ml
1
$249.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Argon charged,Cool Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

application:

It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields and also in the alkylation and alkoxylation of silane.

Specifications

Synonyms
NB6CXG7SPH | A872098 | EINECS 224-851-4 | MKC SILICATE BTS | Glycine, N-[(1, 1-dimethylethoxy)carbonyl]- | SCHEMBL49555 | AKOS015833678 | Butyl silicate | Silane, tetrabutoxy- | Si(OCH2CH2CH2CH3)4 | Tetrabutoxysilane | Silicic acid (H4SiO4), tetrabutyl est
Specifications & Purity
≥98%(GC)
Storage
Room temperature, Argon charged, Cool
Shipped In
Normal
Purity
≥98%(GC)
Names and Identifiers
Pubchem Sid504755296
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504755296
Canonical SmilesCCCCO[Si](OCCCC)(OCCCC)OCCCC
IUPAC Nametetrabutyl silicate
InChIKeyUQMOLLPKNHFRAC-UHFFFAOYSA-N
INCHI1S/C16H36O4Si/c1-5-9-13-17-21(18-14-10-6-2,19-15-11-7-3)20-16-12-8-4/h5-16H2,1-4H3
Isomeric SMILES CCCCO[Si](OCCCC)(OCCCC)OCCCC
PubChem CID 78500
Molecular Weight 320.55

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganometallic compounds
ClassOrganometalloid compounds
SubclassOrganosilicon compounds
Intermediate Tree Nodes Not available
Direct ParentAlkoxysilanes
Alternative Parents Organic metalloid salts  Organooxygen compounds  Organic oxoanionic compounds  Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Alkoxysilane - Organic silicate - Organic metalloid salt - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alkoxysilanes. These are organosilicon compounds with the general formula RO[Si](OR')(R'')(R''') (R,R' = organyl; R'',R''' = any atom).
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeDateItem
D2624315Certificate of AnalysisApr 14, 2026 T161830
D2624314Certificate of AnalysisApr 14, 2026 T161830
D2624313Certificate of AnalysisApr 14, 2026 T161830
A2213537Certificate of AnalysisOct 13, 2025 T161830
I2504634Certificate of AnalysisAug 23, 2025 T161830
I2504635Certificate of AnalysisAug 23, 2025 T161830
I2504643Certificate of AnalysisAug 23, 2025 T161830
C2520804Certificate of AnalysisMar 10, 2025 T161830
G2526046Certificate of AnalysisMar 10, 2025 T161830
C2520806Certificate of AnalysisMar 10, 2025 T161830
C2520805Certificate of AnalysisMar 10, 2025 T161830
A2419716Certificate of AnalysisNov 23, 2023 T161830
A2419715Certificate of AnalysisNov 23, 2023 T161830
A2419714Certificate of AnalysisNov 23, 2023 T161830
A2419713Certificate of AnalysisNov 23, 2023 T161830
A2419712Certificate of AnalysisNov 23, 2023 T161830
A2419711Certificate of AnalysisNov 23, 2023 T161830
K2327134Certificate of AnalysisNov 14, 2023 T161830
K2327065Certificate of AnalysisNov 14, 2023 T161830
K2327066Certificate of AnalysisNov 14, 2023 T161830
G23151200Certificate of AnalysisJun 16, 2023 T161830
G23151198Certificate of AnalysisJun 16, 2023 T161830
G23151196Certificate of AnalysisJun 16, 2023 T161830
G23151195Certificate of AnalysisJun 16, 2023 T161830
A2213540Certificate of AnalysisDec 16, 2021 T161830
A2213533Certificate of AnalysisDec 16, 2021 T161830
A2213497Certificate of AnalysisDec 16, 2021 T161830

Show more ⌵

Chemical and Physical Properties
SolubilityNot miscible or difficult to mix in water.
SensitivityMoisture sensitive
Refractive Index1.4120 to 1.4140
Flash Point(°F)275°F
Flash Point(°C)135℃
Boil Point(°C)275-277 °C
Molecular Weight320.540 g/mol
XLogP3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count16
Exact Mass320.238 Da
Monoisotopic Mass320.238 Da
Topological Polar Surface Area36.900 Ų
Heavy Atom Count21
Formal Charge0
Complexity169.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Ni Yezhou, Shi Xuan, Ma Jun, Jia Zhenhua, Qiu Hua, Chen Kunlin.  (2023)  Facile Synthesis of Chitosan/Nano-silica Microcapsules for Multifunctional Textiles.  JOURNAL OF POLYMERS AND THE ENVIRONMENT,      [PMID:] [10.1007/s10924-023-03135-y]
2. Bo Peng, Jia-Feng Zhou, Hui Chen, Meng Ding, Yi-Song Zhu, Belén Albela, Peng Wu, Laurent Bonneviot, Kun Zhang.  (2023)  Tetraalkoxysilane-Assisted Self-Emulsification Templating for Controlled Mesostructured Silica Nanoparticles.  LANGMUIR,      [PMID:36862534] [10.1021/acs.langmuir.2c03126]
3. Xuejiao Xu, Lijin Huang, Qin Shuai.  (2022)  Porphyrin-based magnetic porous organic polymer for efficient magnetic solid phase extraction of nonsteroidal anti-inflammatory drugs from water.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36638587] [10.1016/j.chroma.2022.463770]
4. Haitao Yu, Yimin Xuan, Qibin Zhu, Sheng Chang.  (2022)  Highly efficient and stable photocatalytic CO2 and H2O reduction into methanol at lower temperatures through an elaborate gas–liquid–solid interfacial system.  GREEN CHEMISTRY,  25  (2): (596-605).  [PMID:] [10.1039/D2GC02869G]
5. Likai Qi, Xinyi Jiang, Ning Wu, Jingjing Li, Bin Di, Fang Yan.  (2022)  Synthesis of a novel polydopamine and C18 dual-functionalized magnetic core-shell mesoporous nanocomposite for enrichment and analysis of widely abused illegal drugs in urine samples on site and in the laboratory.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:35168125] [10.1016/j.jpba.2022.114656]
6. Xu Chong, Zhou Qin, Huang Wei-Ya, Yang Kai, Zhang Yong-Cai, Liang Tong-Xiang, Liu Zhao-Qing.  (2022)  Constructing Z-scheme β-Bi2O3/ZrO2 heterojunctions with 3D mesoporous SiO2 nanospheres for efficient antibiotic remediation via synergistic adsorption and photocatalysis.  RARE METALS,  41  (6): (2094-2107).  [PMID:] [10.1007/s12598-021-01897-9]
7. Yang Wu, Zhiyong Song, Guiyun Deng, Kai Jiang, Huajuan Wang, Xueji Zhang, Heyou Han.  (2021)  Gastric Acid Powered Nanomotors Release Antibiotics for In Vivo Treatment of Helicobacter pylori Infection.  Small,  17  (11): (2006877).  [PMID:33619851] [10.1002/smll.202006877]
8. Juying Lei, Bin Chen, Liang Zhou, Ningkai Ding, Zhengqing Cai, Lingzhi Wang, Su-Il In, Changzheng Cui, Yanbo Zhou, Yongdi Liu, Jinlong Zhang.  (2020)  Efficient degradation of antibiotics in different water matrices through the photocatalysis of inverse opal K-g-C3N4: Insights into mechanism and assessment of antibacterial activity.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2020.125902]
9. Kunlin Chen, Changyue Xu, Jianlin Zhou, Ruoyi Zhao, Qiang Gao, Chaoxia Wang.  (2019)  Multifunctional fabric coatings with slow-releasing fragrance and UV resistant properties from ethyl cellulose/silica hybrid microcapsules.  CARBOHYDRATE POLYMERS,      [PMID:31952616] [10.1016/j.carbpol.2019.115821]
10. Yuejun Jiang, Cong Xu, Yunshi Li, Hong Wang, Lu Liu, Yicheng Ye, Junbin Gao, Hao Tian, Fei Peng, Yingfeng Tu, Yingjia Li.  (2024)  Bottle Nanomotors Amplify Tumor Oxidative Stress for Enhanced Calcium Overload/Chemodynamic Therapy.  Small,      [PMID:38963075] [10.1002/smll.202404402]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.