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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino TFC 007 - Moligand™, ≥98% (HPLC) , Inhibitor of H-PGDS, CAS No.927878-49-7, Inhibitor of H-PGDS
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
N-[4-[4-(4-Morfolinilcarbonil)-1-piperidinil]fenil]-2-fenossi-5-pirimidinecarbossamide
Storage
Conservare a -20°C
Shipped In
Cassetta del ghiaccio + cuscini per il ghiaccio
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Why this grade Moligand™, ≥98% (HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Conservare a -20°C Ships Cassetta del ghiaccio + cuscini per il ghiaccio Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinonimi
N-[4-[4-(4-Morfolinilcarbonil)-1-piperidinil]fenil]-2-fenossi-5-pirimidinecarbossamide
Specifiche e purezza
Moligand™, ≥98% (HPLC)
Meccanismi biochimici e fisiologici
Potente inibitore della prostaglandina D sintasi ematopoietica (H-PGDS) (IC50= 83 nM). Inibisce la produzione di PGD2 e il blocco nasale in fase avanzata in un modello animale di rinite allergica. Presenta effetti trascurabili su COX-1, COX-2, 5-LOX, LTC4
Condizioni di conservazione di stoccaggio
Conservare a -20°C
Spedito in
Cassetta del ghiaccio + cuscini per il ghiaccio
Meccanismo d'azione
Inhibitor of H-PGDS
Nomi e identificatori Pubchem Sid 528767385 Sorrisi canonici C1CN(CCC1C(=O)N2CCOCC2)C3=CC=C(C=C3)NC(=O)C4=CN=C(N=C4)OC5=CC=CC=C5 IUPAC Name N-[4-[4-(morpholine-4-carbonyl)piperidin-1-yl]phenyl]-2-phenoxypyrimidine-5-carboxamide InChIKey NLSSUSRERAMBTA-UHFFFAOYSA-N INCHI 1S/C27H29N5O4/c33-25(21-18-28-27(29-19-21)36-24-4-2-1-3-5-24)30-22-6-8-23(9-7-22)31-12-10-20(11-13-31)26(34)32-14-16-35-17-15-32/h1-9,18-20H,10-17H2,(H,30,33) Isomeri SMILES C1CN(CCC1C(=O)N2CCOCC2)C3=CC=C(C=C3)NC(=O)C4=CN=C(N=C4)OC5=CC=CC=C5 PubChem CID 16040067 Peso molecolare 487.55
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Anilides Intermediate Tree Nodes Not available Direct Parent Aromatic anilides Alternative Parents Phenylpiperidines Diarylethers Pyrimidinecarboxamides Piperidinecarboxamides Aniline and substituted anilines Dialkylarylamines Phenoxy compounds Phenol ethers Morpholines Heteroaromatic compounds Tertiary carboxylic acid amides Amino acids and derivatives Secondary carboxylic acid amides Oxacyclic compounds Dialkyl ethers Azacyclic compounds Hydrocarbon derivatives Carbonyl compounds Organic oxides Molecular Framework Aromatic heteromonocyclic compounds Substituents Aromatic anilide - Phenylpiperidine - Diaryl ether - Piperidinecarboxamide - Pyrimidinecarboxamide - Pyrimidine-5-carboxylic acid or derivatives - Phenoxy compound - Phenol ether - Tertiary aliphatic/aromatic amine - Aniline or substituted anilines - Dialkylarylamine - Morpholine - Oxazinane - Piperidine - Pyrimidine - Heteroaromatic compound - Tertiary carboxylic acid amide - Secondary carboxylic acid amide - Tertiary amine - Carboxamide group - Amino acid or derivatives - Organoheterocyclic compound - Oxacycle - Azacycle - Carboxylic acid derivative - Dialkyl ether - Ether - Carbonyl group - Amine - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound Descrizione This compound belongs to the class of organic compounds known as aromatic anilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with an aromatic group. They have the general structure RNC(=O)R', where R= benzene, and R = aryl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Solubilità Solvent:DMSO, Max Conc. mg/mL: 48.76, Max Conc. mM: 100 Peso molecolare 487.500 g/mol XLogP3 2.600 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 6 Exact Mass 487.222 Da Monoisotopic Mass 487.222 Da Topological Polar Surface Area 96.900 Ų Heavy Atom Count 36 Formal Charge 0 Complexity 703.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Recensioni Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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