TLR2 Mouse mAb - Anticorpo primario, specific to TLR2, Mouse IgG1

Cat. No.: Ab131480

QUALITÀ & PUREZZA Carrier Free, ExactAb™, Validated, High Performance, See COA

Application

WB

Host species

Mouse

Reactive species

Umano

Isotype

Mouse IgG1

Clone Number

C9

Conjugation

Unconjugated

Panoramica

Mouse anti Human TLR2 Antibody, Monoclonal (C9), could be used for WB and so on. Application WB: 0.01-2 µg/mL

Protein Function

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Specifiche

Product Name

TLR2 Mouse mAb - Anticorpo primario, specific to TLR2, Mouse IgG1

Sinonimi

CD282 antibody|CD282 antigen antibody|TIL 4 antibody|TIL4 antibody|TLR 2 antibody|TLR2 antibody|Toll like receptor 2 antibody|Toll like receptor 2 precursor antibody|Toll-like receptor 2 antibody|Toll/interleukin 1 receptor like 4 antibody|Toll/interleukin 1 receptor like protein 4 antibody|Toll/interleukin receptor like protein 4 antibody|Toll/interleukin-1 receptor-like protein 4 antibody|CD282 antigen|CD282|TIL4CD282|TLR2|toll/interleukin 1 receptor-like 4|Toll/interleukin-1 receptor-like protein 4|toll-like receptor 2

Specifiche e purezza

Carrier Free, ExactAb™, Validated, High Performance, See COA

Specie ospite

Mouse

Specificità

TLR2

Immunogeno

Recombinant TLR2 expressed in E.coli (AA 47-245)

Controllo positivo

WB: Human milk lysate.

Coniugazione

Unconjugated

Grado

Carrier Free, ExactAb™, High Performance, Validated

Isotipo

Mouse IgG1

Tipo di catena leggera

kappa

SDS-PAGE

150 kDa

Metodo di purificazione

Protein A + Protein G purified

Concentrazione

See COA

Product Line

Prodotti biologici

Stoccaggio e spedizione

Forma

Liquid

Condizioni di conservazione di stoccaggio

Store at -20°C,Avoid repeated freezing and thawing

Spedito in

Ice chest + Ice pads

Stabilità e conservazione

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Immagini

Western Blot: TLR2 Mouse mAb (Ab131480)

TLR2 Mouse mAb (Ab131480) - Western Blot
All lanes: TLR2 Mouse mAb (Ab131480) at 1/1000 dilution
Samples: Lysates at 20 µL per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/10000 dilution

Predicted band size: 90 kDa
Observed band size: 92 kDa
Exposure time: 95.6 s

Applicazione

Applicazione

Dilution info

WB

0.01-2 µg/mL

Obiettivi associati (umani)

TLR2 Tchem Toll-like receptor 2 (0 Activities)

Discover Target: TLR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TLR2 Tchem Toll-like receptor 2 (975 Activities)

Discover Target: TLR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TLR2 Tchem TLR2/TLR6 (50 Activities)

Discover Target: TLR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Domande frequenti

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (TLR2 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.