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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino TP-3654 - 10mM in DMSO , CAS No.1361951-15-6
GRADE & PURITY 10mM in DMSO
Synonyms
IndoFast Orange Lake OV 6014 | SB17245 | BCP30070 | A857573 | BDBM242374 | TP 3654 | SCHEMBL20794171 | CHEBI:180578 | TP3654; TP 3654 | FT-0649638 | XRNVABDYQLHODA-SKHKEOPYSA-N | EX-A1828 | NCGC00511354-02 | EOB0N7BOY4 | UNII-EOB0N7BOY4 | SCHEMBL22421478
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica Information
TP-3654 is the second-generationPIMinhibitor with Kivalues of 5 nM, 239 nM, and 42 nM for PIM-1, PIM-2 and PIM-3, respectively.
Targets
Pim1 (Cell-free assay); Pim3 (Cell-free assay); Pim2 (Cell-free assay) 5 nM(Ki); 42 nM(Ki); 239 nM(Ki)
Specifications Sinonimi
IndoFast Orange Lake OV 6014 | SB17245 | BCP30070 | A857573 | BDBM242374 | TP 3654 | SCHEMBL20794171 | CHEBI:180578 | TP3654; TP 3654 | FT-0649638 | XRNVABDYQLHODA-SKHKEOPYSA-N | EX-A1828 | NCGC00511354-02 | EOB0N7BOY4 | UNII-EOB0N7BOY4 | SCHEMBL22421478
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
TP-3654 is the second-generation PIM inhibitor with Ki values of 5 nM, 239 nM, and 42 nM for PIM-1, PIM-2 and PIM-3, respectively.
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Proprietà del prodotto ALogP 4.874 Conteggio HBD 1 Legame rotabile 5
Nomi e identificatori Pubchem Sid 528767425 Sorrisi canonici CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O IUPAC Name 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol InChIKey XRNVABDYQLHODA-UHFFFAOYSA-N INCHI 1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28) Isomeri SMILES CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O PubChem CID 66598080 Peso molecolare 418.46
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Azoles Subclass Imidazoles Intermediate Tree Nodes Substituted imidazoles Direct Parent Phenylimidazoles Alternative Parents Trifluoromethylbenzenes Secondary alkylarylamines Aminopyridazines N-substituted imidazoles Imidolactams Tertiary alcohols Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organofluorides Hydrocarbon derivatives Alkyl fluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents 4-phenylimidazole - 5-phenylimidazole - Trifluoromethylbenzene - Secondary aliphatic/aromatic amine - Aminopyridazine - Imidolactam - Benzenoid - Pyridazine - N-substituted imidazole - Monocyclic benzene moiety - Heteroaromatic compound - Tertiary alcohol - Azacycle - Secondary amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Alkyl halide - Alkyl fluoride - Alcohol - Aromatic heteropolycyclic compound Descrizione This compound belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche DMSO (mg/mL) Solubilità massima 84 DMSO (mM) Solubilità massima 200.736032117765 Acqua (mg/mL) Solubilità massima ＜1 Peso molecolare 418.500 g/mol XLogP3 4.600 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 4 Exact Mass 418.198 Da Monoisotopic Mass 418.198 Da Topological Polar Surface Area 62.500 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 579.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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