Triacsin C - Moligand™,≥94%,from Streptomyces aureofaciens , CAS No.76896-80-5

CAS: 76896-80-5 Cat. No.: T139793 Formula: C₁₁H₁₇N₃O Peso molecolare: 207.27 PubChem CID: 9576787

GRADE & PURITY Moligand™, ≥94%, from Streptomyces aureofaciens

Synonyms

2,4,7-Undecatrienal nitrosohydrazone | WS 1228A;FR 900190 | 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene | 2,4,7-Undecatrienal, nitrosohydrazone, (E,E,E)- | (2E,4E,7E)-undecatrienal nitrosohydrazone | FR-900190 | (2E,4E,7E)-2,4,7-Undecatrienal nitros

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Panoramica

Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator.

Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates IC50=3.6-8.7 μM1–3. Inhibits neutrophil functions

Specifications

Sinonimi

2,4,7-Undecatrienal nitrosohydrazone | WS 1228A;FR 900190 | 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene | 2,4,7-Undecatrienal, nitrosohydrazone, (E,E,E)- | (2E,4E,7E)-undecatrienal nitrosohydrazone | FR-900190 | (2E,4E,7E)-2,4,7-Undecatrienal nitros

Specifiche e purezza

Moligand™,≥94%,from Streptomyces aureofaciens

Meccanismi biochimici e fisiologici

Triacsin C is a potent inhibitor of long-chain fatty acyl-CoA synthetase. It can block fatty acid-induced β-cell apoptosis (adipocyte apoptosis) in obese rat models. Additionally, it inhibits the de novo synthesis of triglycerides, diglycerides, and chole

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥94%

Nomi e identificatori

Pubchem Sid

528767537

Sorrisi canonici

CCCC=CCC=CC=CC=NNN=O

IUPAC Name

N-[(E)-[(2E,4E,7E)-undeca-2,4,7-trienylidene]amino]nitrous amide

InChIKey

NKTGCVUIESDXPU-YLEPRARLSA-N

INCHI

1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+

Isomeri SMILES

CCC/C=C/C/C=C/C=C/C=N/NN=O

WGK Germania

3

PubChem CID

9576787

Peso molecolare

207.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Organic nitroso compounds

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Organic nitroso compounds
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic N-nitroso compounds
• Alternative Parents: Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic n-nitroso compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as organic n-nitroso compounds. These are organic compounds containing a n-nitroso group -NN=O.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (non umani)

Rotavirus (147 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO (25 mg/ml), and methanol (5 mg/ml).
• Sensibilità: Sensitive to light; sensitive to humidity
• Peso molecolare: 207.270 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 207.137 Da
• Monoisotopic Mass: 207.137 Da
• Topological Polar Surface Area: 53.800 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 255.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1