Trichostatin A - Moligand™, 10 mM in DMSO , CAS No.58880-19-6

CAS: 58880-19-6 Cat. No.: T1497755 Molecular Weight: 302.37 EC Number: 611-758-2 PubChem CID: 444732
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
T1497755-1ml
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$261.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Trichostatin A (TSA) is a potent and specific inhibitor of HDAC class I/II , with an IC 50 value of 1.8 nM for HDAC.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
WGK Germany 3
RTECS MI5215000
PubChem CID 444732
Molecular Weight 302.37
Reaxy-Rn 2391788

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α]136° (C=0.3,MeOH)
Melt Point(°C)144 °C(dec.)
Documents & Articles
Citations of This Product
References
1. Pengfei Zhang, Xinyu Chen, Fanqiang Bu, Chen Chen, Lifei Huang, Zixu Xie, Guofeng Li, Xing Wang.  (2023)  Dual Coordination between Stereochemistry and Cations Endows Polyethylene Terephthalate Fabrics with Diversiform Antimicrobial Abilities for Attack and Defense.  ACS Applied Materials & Interfaces,      [PMID:36774642] [10.1021/acsami.2c19323]
2. Rui Li, Li Xie, Lei Li, Xiaojiao Chen, Tong Yao, Yuanxin Tian, Qingping Li, Kai Wang, Chenyang Huang, Cui Li, Yifan Li, Hongwei Zhou, Neil Kaplowitz, Yong Jiang, Peng Chen.  (2021)  The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice.  Acta Pharmaceutica Sinica B,      [PMID:35127379] [10.1016/j.apsb.2021.05.029]
3. Bo-Yu Peng, Yiming Su, Zhibin Chen, Jiabin Chen, Xuefei Zhou, Mark Eric Benbow, Craig S. Criddle, Wei-Min Wu, Yalei Zhang.  (2019)  Biodegradation of Polystyrene by Dark (Tenebrio obscurus) and Yellow (Tenebrio molitor) Mealworms (Coleoptera: Tenebrionidae).  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:30990998] [10.1021/acs.est.8b06963]
4. Yue Xu, Hang Gao, Yan Shen, Shigan Chai, Jinzhi Zhang, Qichao Zou.  (2017)  Application of Gemini quaternary ammonium with ester groups in cationic P(St-co-BA) nanolatex and study on its antibacterial properties.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:28866183] [10.1016/j.msec.2017.06.010]
5. Fan Yanan, Xu Qixiang, Ren Keyu, Zhai Mengge, Xing Guozheng, Song Yishan, Zhu Yongheng.  (2024)  Research on pH-responsive Antibacterial Materials Using Citral-modified Zinc Oxide Nanoparticles.  Food Quality and Safety,      [PMID:] [10.1093/fqsafe/fyae010]
6. Suifei Li, Junyang Zhong, Yunxiao Ma, Chengfeng Yue, Wenxia Lv, Guodong Ye, Xiumei Tian, Xin Li, Yugang Huang, Lingran Du.  (2025)  Influences of chain length and conformation of guanidinylated linear synthetic polypeptides on nuclear delivery of siRNA with potential application in transcriptional gene silencing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40180092] [10.1016/j.ijbiomac.2025.142743]
7. Wang Rui, Zou Ziwei, An Yi, Wang Liulin, Li Chengyin, Zou Yinshui, Wang Guangzhi.  (2026)  PINK1 deacetylation by emodin-induced SIRT3 upregulation alleviates acute kidney injury by Inhibition of ferroptosis.  INFLAMMATION RESEARCH,  75  (1): (37).  [PMID:41703345] [10.1007/s00011-025-02137-x]
8. Ke Li, Zhengxiang Wang, Zaigang Zhou, Huan Ding, Sheng Wu, Yuan Li, Jianliang Shen.  (2026)  Mitochondria-Targeting Nanocuproptosis Breaks Immune Resistance.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202528750]
9. Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji.  (2026)  DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,  57  (4): (1-13).  [PMID:41789628] [10.3892/ijmm.2026.5776]
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