Trichostatin A - Moligand™, 10 mM in DMSO , CAS No.58880-19-6

CAS: 58880-19-6 Cat. No.: T1497755 Formula: C₁₇H₂₂N₂O₃ Peso molecolare: 302.37 Numero EC: 611-758-2 PubChem CID: 444732

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Trichostatin A (TSA) is a potent and specific inhibitor of HDAC class I/II , with an IC 50 value of 1.8 nM for HDAC.

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
• WGK Germania: 3
• RTECS: MI5215000
• PubChem CID: 444732
• Peso molecolare: 302.37
• Reaxy-Rn: 2391788

Proprietà chimiche e fisiche

• Rotazione specifica [α]: 136° (C=0.3,MeOH)
• Punto di fusione (°C): 144 °C(dec.)

Riferimenti

1. Pengfei Zhang, Xinyu Chen, Fanqiang Bu, Chen Chen, Lifei Huang, Zixu Xie, Guofeng Li, Xing Wang.  (2023)  Dual Coordination between Stereochemistry and Cations Endows Polyethylene Terephthalate Fabrics with Diversiform Antimicrobial Abilities for Attack and Defense.  ACS Applied Materials & Interfaces,      [PMID:36774642] [10.1021/acsami.2c19323]

2. Rui Li, Li Xie, Lei Li, Xiaojiao Chen, Tong Yao, Yuanxin Tian, Qingping Li, Kai Wang, Chenyang Huang, Cui Li, Yifan Li, Hongwei Zhou, Neil Kaplowitz, Yong Jiang, Peng Chen.  (2021)  The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice.  Acta Pharmaceutica Sinica B,      [PMID:35127379] [10.1016/j.apsb.2021.05.029]

3. Bo-Yu Peng, Yiming Su, Zhibin Chen, Jiabin Chen, Xuefei Zhou, Mark Eric Benbow, Craig S. Criddle, Wei-Min Wu, Yalei Zhang.  (2019)  Biodegradation of Polystyrene by Dark (Tenebrio obscurus) and Yellow (Tenebrio molitor) Mealworms (Coleoptera: Tenebrionidae).  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:30990998] [10.1021/acs.est.8b06963]

4. Yue Xu, Hang Gao, Yan Shen, Shigan Chai, Jinzhi Zhang, Qichao Zou.  (2017)  Application of Gemini quaternary ammonium with ester groups in cationic P(St-co-BA) nanolatex and study on its antibacterial properties.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:28866183] [10.1016/j.msec.2017.06.010]

5. Fan Yanan, Xu Qixiang, Ren Keyu, Zhai Mengge, Xing Guozheng, Song Yishan, Zhu Yongheng.  (2024)  Research on pH-responsive Antibacterial Materials Using Citral-modified Zinc Oxide Nanoparticles.  Food Quality and Safety,      [PMID:] [10.1093/fqsafe/fyae010]

6. Suifei Li, Junyang Zhong, Yunxiao Ma, Chengfeng Yue, Wenxia Lv, Guodong Ye, Xiumei Tian, Xin Li, Yugang Huang, Lingran Du.  (2025)  Influences of chain length and conformation of guanidinylated linear synthetic polypeptides on nuclear delivery of siRNA with potential application in transcriptional gene silencing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40180092] [10.1016/j.ijbiomac.2025.142743]

7. Wang Rui, Zou Ziwei, An Yi, Wang Liulin, Li Chengyin, Zou Yinshui, Wang Guangzhi.  (2026)  PINK1 deacetylation by emodin-induced SIRT3 upregulation alleviates acute kidney injury by Inhibition of ferroptosis.  INFLAMMATION RESEARCH,  75  (1): (37).  [PMID:41703345] [10.1007/s00011-025-02137-x]

8. Ke Li, Zhengxiang Wang, Zaigang Zhou, Huan Ding, Sheng Wu, Yuan Li, Jianliang Shen.  (2026)  Mitochondria-Targeting Nanocuproptosis Breaks Immune Resistance.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202528750]

9. Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji.  (2026)  DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,  57  (4): (1-13).  [PMID:41789628] [10.3892/ijmm.2026.5776]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 58880-19-6, the molecular formula is C17H22N2O3, and the molecular weight is 302.37 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.