TT-10 , CAS No.2230640-94-3

CAS: 2230640-94-3 Cat. No.: T657027 PubChem CID: 134827875

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss.

Form:Solid

In Vitro:TT-10 (48 h) markedly promotes cell cycle activation and increased cell division of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hiPSCMs). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

Meccanismi biochimici e fisiologici

TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Sorrisi canonici: C=CCNC1=NC(=C(S1)C(=O)C2=CC=C(S2)F)N
• IUPAC Name: [4-amino-2-(prop-2-enylamino)-1,3-thiazol-5-yl]-(5-fluorothiophen-2-yl)methanone
• InChIKey: GVYPHJQPOHDZEI-UHFFFAOYSA-N
• INCHI: 1S/C11H10FN3OS2/c1-2-5-14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h2-4H,1,5,13H2,(H,14,15)
• PubChem CID: 134827875

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Azoles
      • Subclass Thiazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Azoles
• Subclass: Thiazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,4,5-trisubstituted thiazoles
• Alternative Parents: Thiophene carboxylic acids and derivatives Aryl ketones Secondary alkylarylamines 2,5-disubstituted thiophenes Imidolactams Alpha-branched alpha,beta-unsaturated ketones Vinylogous amides Heteroaromatic compounds Enones Acryloyl compounds Thioenol ethers Vinyl fluorides Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Fluoroalkenes Carboximidamides Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aryl ketone - Thiophene carboxylic acid or derivatives - 2,4,5-trisubstituted 1,3-thiazole - 2,5-disubstituted thiophene - Secondary aliphatic/aromatic amine - Imidolactam - Alpha-branched alpha,beta-unsaturated-ketone - Heteroaromatic compound - Vinylogous amide - Alpha,beta-unsaturated ketone - Thiophene - Enone - Acryloyl-group - Thioenolether - Ketone - Azacycle - Fluoroalkene - Haloalkene - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Carboximidamide - Vinyl halide - Vinyl fluoride - Secondary amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Primary aliphatic amine - Amine - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as 2,4,5-trisubstituted thiazoles. These are compounds containing a thiazole ring substituted at positions 2, 4 and 5 only.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Domande frequenti

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2230640-94-3. InChIKey GVYPHJQPOHDZEI-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.