UK-371804 HCl - ≥97% , CAS No.256476-36-5

CAS: 256476-36-5 Cat. No.: U414017 Formula: C₁₄H₁₇Cl₂N₅O₄S Peso molecolare: 422.29 PubChem CID: 16657953

QUALITÀ & PUREZZA ≥97%

Synonyms

Alanine,N-​[[1-​[(aminoiminomethyl)​amino]​-​4-​chloro-​7-​isoquinolinyl]​sulfonyl]​-​2-​methyl-​,hydrochloride (1:1)

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifiche

Sinonimi

Alanine,N-​[[1-​[(aminoiminomethyl)​amino]​-​4-​chloro-​7-​isoquinolinyl]​sulfonyl]​-​2-​methyl-​,hydrochloride (1:1)

Specifiche e purezza

≥97%

Meccanismi biochimici e fisiologici

UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥97%

Nomi e identificatori

Pubchem Sid

504768473

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504768473

Sorrisi canonici

CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl.Cl

IUPAC Name

2-[[4-chloro-1-(diaminomethylideneamino)isoquinolin-7-yl]sulfonylamino]-2-methylpropanoic acid;hydrochloride

InChIKey

IUBFETAFRGVODB-UHFFFAOYSA-N

INCHI

1S/C14H16ClN5O4S.ClH/c1-14(2,12(21)22)20-25(23,24)7-3-4-8-9(5-7)11(19-13(16)17)18-6-10(8)15;/h3-6,20H,1-2H3,(H,21,22)(H4,16,17,18,19);1H

Isomeri SMILES

CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl.Cl

PubChem CID

16657953

Peso molecolare

422.29

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 42 mg/mL warmed with 50ºC Water: bath (99.45 mM); Water: Insoluble; Ethanol: Insoluble
• Sensibilità: Light sensitive
• Peso molecolare: 422.300 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 421.038 Da
• Monoisotopic Mass: 421.038 Da
• Topological Polar Surface Area: 169.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 644.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Domande frequenti

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 256476-36-5, the molecular formula is C14H17Cl2N5O4S, and the molecular weight is 422.29 g/mol. InChIKey IUBFETAFRGVODB-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.