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· · COA & SDS available for every product · Same-day shipping on in-stock items Uprifosbuvir , Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor, CAS No.1496551-77-9, Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Synonyms
DB15206 | D-Alanine, N-((P(R),2'R)-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl)-, 1- methylethyl ester | propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoat
Shipped In
Ice chest + Ice pads
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Why this grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus.
Form:Solid
Specifications Synonyms
DB15206 | D-Alanine, N-((P(R), 2'R)-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl)-, 1- methylethyl ester | propan-2-yl (2R)-2-[[[(2R, 3R, 4R, 5R)-4-chloro-5-(2, 4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoat
Biochemical and Physiological Mechanisms
Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Product Properties Names and Identifiers Canonical Smiles CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)Cl)O)OC3=CC=CC=C3 IUPAC Name propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate InChIKey SFPFZQKYPOWCSI-KHFYHRBSSA-N INCHI 1S/C22H29ClN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16-,18-,20-,22-,36-/m1/s1 Isomeric SMILES C[C@H](C(=O)OC(C)C)N[P@@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)Cl)O)OC3=CC=CC=C3 Alternate CAS 1496551-77-9 PubChem CID 90055716 MeSH Entry Terms MK-3682;uprifosbuvir Molecular Weight 545.91
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Nucleosides, nucleotides, and analogues Class Pyrimidine nucleosides Subclass Pyrimidine 2'-deoxyribonucleosides Intermediate Tree Nodes Not available Direct Parent Pyrimidine 2'-deoxyribonucleosides Alternative Parents Alpha amino acid esters Alanine and derivatives Phosphoric diester monoamides Phenoxy compounds Pyrimidones Hydropyrimidines Organic phosphoramides Vinylogous amides Oxolanes Heteroaromatic compounds Ureas Secondary alcohols Carboxylic acid esters Chlorohydrins Lactams Oxacyclic compounds Azacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Alkyl chlorides Organonitrogen compounds Carbonyl compounds Organic oxides Organochlorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Pyrimidine 2'-deoxyribonucleoside - Alpha-amino acid ester - Alanine or derivatives - Alpha-amino acid or derivatives - Phenoxy compound - Phosphoric diester monoamide - Pyrimidone - Monocyclic benzene moiety - Hydropyrimidine - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Organic phosphoric acid amide - Benzenoid - Heteroaromatic compound - Oxolane - Vinylogous amide - Urea - Secondary alcohol - Carboxylic acid ester - Chlorohydrin - Halohydrin - Lactam - Organoheterocyclic compound - Azacycle - Oxacycle - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Alkyl chloride - Hydrocarbon derivative - Organohalogen compound - Alcohol - Organochloride - Organonitrogen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Alkyl halide - Organooxygen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. These are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 545.900 g/mol XLogP3 1.200 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 10 Rotatable Bond Count 11 Exact Mass 545.133 Da Monoisotopic Mass 545.133 Da Topological Polar Surface Area 153.000 Ų Heavy Atom Count 36 Formal Charge 0 Complexity 913.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 6 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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