Urocortin II (mouse)（TFA） - ≥95% , CAS No.330648-32-3(free)

CAS: 330648-32-3(free) Cat. No.: U274708 Formula: C₁₈₇ H₃₂₀N₅₆O₅₀(free) Peso molecolare: 4152.96(free)

GRADE & PURITY ≥95%

Storage

Store at 2-8°C

Shipped In

Wet ice

Panoramica

Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow.

Specifications

Specifiche e purezza

≥95%

Meccanismi biochimici e fisiologici

Selective CRFR2β agonist. Urocontin ( Asc 2962 ) homolog. Induces ERK1/2 phosphorylation and cAMP stimulation. Shows central autonomic, appetitive control and cardioprotective effects in vivo.

Condizioni di conservazione di stoccaggio

Store at 2-8°C

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥95%

Nomi e identificatori

Peso molecolare

4152.96(free)

Proprietà chimiche e fisiche

• Solubilità: Soluble in water