UTP is Uridine-5'-triphosphate, Chinese name is uridine-5'-triphosphate, which can be used in various related applications in molecular biology, such as in vitro transcription, siRNA synthesis, etc. UTP is also involved in galactose metabolism, in which the activated form of UDP-galactose is converted to UDP-glucose, which enters the glycogen synthesis pathway. This product is an aqueous solution of UTP sodium salt with a purity of ≥ 99% (HPLC) at a concentration of 100mM±5mM, and is free of endonuclease, exonuclease and ribonuclease contamination.
This product is produced with raw and auxiliary materials of pharmaceutical specifications, and all kinds of pollution in the production process are strictly controlled. Product production and quality management procedures in line with GMP standards ensure the traceability of the production process and all raw and auxiliary materials.
Quality requirements
| project |
standard |
| appearance |
Clear liquid |
| Visible foreign matter |
Compliance with regulations |
| purity |
≥ 99%
|
| Endonuclease residues |
Degradation of substrate shall not exceed 10% |
| Exonuclease residues |
Degradation of substrate shall not exceed 10% |
| RNase residue |
Degradation of substrate shall not exceed 10% |
| Bacterial endotoxin content |
≤1EU/mg |
| Mycoplasma detection |
negative |
| Heavy metal residues |
≤10ppm |
|
Produced according to the following specifications
1. ISO 9001:2015, certified facility.
2. "GMP Appendix - Cell Therapy Products" State Drug Administration.
3. "General Introduction to Human Gene Therapy - Chinese Pharmacopoeia 2020" National Pharmacopoeia Commission.
4. USP Chapter <1043>, Ancillary Materials for Cell, Gene, and Tissue-Engineered Products
5. USP Chapter <92>, Growth Factors and Cytokines Used in Cell Therapy Manufacturing
6. Ph. Eur. General Chapter 5.2.12, Raw Materials of Biological Origin for the Production of Cell-based and Gene Therapy Medicinal Products
Storage temperature
The product can be stored or transported at -20±5℃ for a short period of time, and it can be stored at -70±5℃ for a long time, and the product is valid for 1 years;
Avoid multiple freeze-thaw cycles and frequent temperature changes;
Concentration gradients may form after the product is frozen and should be thoroughly mixed before use.
F2523644