Vimentin-IN-1 - Moligand™, 10 mM in DMSO , CAS No.2319587-80-7
Disponibile
SKU
V1497752
Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin ( VIM ), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1.
Maggiori Informazioni
| CAS | 2319587-80-7 |
|---|---|
| Concentrazione | 10 mM in DMSO |
| Specifiche e purezza | Moligand™, 10 mM in DMSO |
| Condizioni di conservazione di stoccaggio | Store at -80°C |
| Spedito in | Dry ice packs + Cold packs |
| Product Description | Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin ( VIM ), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1. |
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