Visnagin - Moligand™,≥99% , Antagonist of A 2A receptor;Antagonist of A 3 receptor, CAS No.82-57-5, Antagonist of A 2A receptor;Antagonist of A 3 receptor

CAS: 82-57-5 Cat. No.: V614754 Formula: C₁₃H₁₀O₄ Peso molecolare: 230.22 Numero EC: 201-430-3 PubChem CID: 6716

QUALITÀ & PUREZZA Moligand™, ≥99%

Synonyms

FUK-724|5-Methoxy-2-methylfuranochromone|SDCCGMLS-0066603.P001|5H-Furo[3,2-g][1]benzopyran-5-one, 4-methoxy-7-methyl-|4-METHOXY-7-METHYL-5H-FURO(3,2-G)(1)BENZOPYRAN-5-ONE|4-Methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one #|4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one|4-Methoxy-7-methyl-5H-furo[3,2-g]-1-benzopyran-5-one|4-Methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one|Visnagidin|4-Methoxy-7-methylfuro(3,2-g)chromen-5-one|Visnagin|4-methoxy-7-methylpyrano[3,2-f][1]benzoxol-5-one|4-Methoxy-7-methyl-5H-furo(3,2-g)(1)-benzopyran-5-one|5H-Furo[3, 4-methoxy-7-methyl-|Desmethoxykhellin; NSC 100593; Visnagidin; Visnagine|Visnagine|5H-FURO(3,2-g)(1)BENZOPYRAN-5-ONE, 4-METHOXY-7-METHYL-|VISNAGIN [MI]|5H-Furo[3,2-g][1]benzopyran-5-one,4-methoxy-7-methyl-|Desmethoxykhellin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles.

Specifiche

Sinonimi

FUK-724 | 5-Methoxy-2-methylfuranochromone | SDCCGMLS-0066603.P001 | 5H-Furo[3,2-g][1]benzopyran-5-one, 4-methoxy-7-methyl- | 4-METHOXY-7-METHYL-5H-FURO(3,2-G)(1)BENZOPYRAN-5-ONE | 4-Methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one # | 4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | 4-Methoxy-7-methyl-5H-furo[3,2-g]-1-benzopyran-5-one | 4-Metho Mostra altro

Specifiche e purezza

Moligand™,≥99%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

ANTAGONIST

Meccanismo d'azione

Antagonist of A 2A receptor;Antagonist of A 3 receptor

Purezza

≥99%

Nomi e identificatori

Pubchem Sid

528776733

Sorrisi canonici

CC1=CC(=O)C2=C(O1)C=C3C(=C2OC)C=CO3

IUPAC Name

4-methoxy-7-methylfuro[3,2-g]chromen-5-one

InChIKey

NZVQLVGOZRELTG-UHFFFAOYSA-N

INCHI

1S/C13H10O4/c1-7-5-9(14)12-11(17-7)6-10-8(3-4-16-10)13(12)15-2/h3-6H,1-2H3

Isomeri SMILES

CC1=CC(=O)C2=C(O1)C=C3C(=C2OC)C=CO3

CAS alternativo

82-57-5

PubChem CID

6716

Numero NSC

100593

Termini MeSH

visnagin

Peso molecolare

230.22

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Chromones
          • Level6 Furanochromones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Chromones
• Direct Parent: Furanochromones
• Alternative Parents: Benzofurans Anisoles Pyranones and derivatives Alkyl aryl ethers Vinylogous esters Heteroaromatic compounds Furans Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Furanochromone - Benzofuran - Anisole - Alkyl aryl ether - Pyranone - Benzenoid - Pyran - Heteroaromatic compound - Vinylogous ester - Furan - Ether - Oxacycle - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as furanochromones. These are polycyclic aromatic compounds containing a furan ring fused to a 1-benzopyran-4-one ring system.
• External Descriptors: Benzopyranoids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

ADORA2A Tclin Adenosine receptor A2a (1 Activities)

Discover Target: ADORA2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 (1 Activities)

Discover Target: ADORA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA2A Tclin Adenosine A2a receptor (16305 Activities)

Discover Target: ADORA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

Discover Target: ADORA3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine receptors; A1 & A3 (1051 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

Discover Target: TARDBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Adora2b Adenosine A2 receptor (1828 Activities)

Discover Target: Adora2b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 230.220 g/mol
• XLogP3: 2.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 230.058 Da
• Monoisotopic Mass: 230.058 Da
• Topological Polar Surface Area: 48.700 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 362.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1