Visomitin (SKQ1) - ≥96% , CAS No.934826-68-3

CAS: 934826-68-3 Cat. No.: V420065 Formula: C₃₆H₄₂BrO₂P Peso molecolare: 617.6 PubChem CID: 16679091

GRADE & PURITY ≥96%

Synonyms

SKQ1(Visomitin) | UNII-7B14500J3E | MFCD29477502 | 934826-68-3 (bromide) | 2,3-Dimethyl-5-(10-(triphenyl-L-5-phosphanyl)decyl)-1,4-benzoquinone hydrobromide | 7B14500J3E | AKOS037515539 | SKQ1 bromide | SKQ-1 bromide | Visomitin (SKQ1) | (10-(4,5-dimethyl

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Product introduction：

Visomitin is a new antioxidant with the highest mitochondrion membrane penetrating ability and potent antioxidant capability.

Direct treatment of tumor infiltrating leukocytes with Visomitin (SkQ1) does not influence their cytotoxicity against Panc02 cells. While Visomitin does not affect viability of the cell lines, this drug at 500 nM concentration reduces heavily the proliferation of human PDAC cells.

Specifications

Sinonimi

SKQ1(Visomitin) | UNII-7B14500J3E | MFCD29477502 | 934826-68-3 (bromide) | 2,3-Dimethyl-5-(10-(triphenyl-L-5-phosphanyl)decyl)-1,4-benzoquinone hydrobromide | 7B14500J3E | AKOS037515539 | SKQ1 bromide | SKQ-1 bromide | Visomitin (SKQ1) | (10-(4,5-dimethyl

Specifiche e purezza

≥96%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥96%

Nomi e identificatori

Pubchem Sid

504768481

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504768481

Sorrisi canonici

CC1=C(C(=O)C(=CC1=O)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

IUPAC Name

10-(4,5-dimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl-triphenylphosphanium;bromide

InChIKey

WYHFWTRUGAFNKW-UHFFFAOYSA-M

INCHI

1S/C36H42O2P.BrH/c1-29-30(2)36(38)31(28-35(29)37)20-12-7-5-3-4-6-8-19-27-39(32-21-13-9-14-22-32,33-23-15-10-16-24-33)34-25-17-11-18-26-34;/h9-11,13-18,21-26,28H,3-8,12,19-20,27H2,1-2H3;1H/q+1;/p-1

Isomeri SMILES

CC1=C(C(=O)C(=CC1=O)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

PubChem CID

16679091

Peso molecolare

617.6

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Phenylphosphines and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Phenylphosphines and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylphosphines and derivatives
• Alternative Parents: P-benzoquinones Alpha-branched alpha,beta-unsaturated ketones Enones Acryloyl compounds Organopnictogen compounds Organophosphorus compounds Organic oxides Organic bromide salts Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Triphenylphosphine - Quinone - P-benzoquinone - Phenylphosphine - Alpha-branched alpha,beta-unsaturated-ketone - Alpha,beta-unsaturated ketone - Enone - Acryloyl-group - Cyclic ketone - Ketone - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic bromide salt - Organic salt - Organophosphorus compound - Organooxygen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as phenylphosphines and derivatives. These are compounds containing a phenylphosphine, which consists of phosphine substituent bound to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: DMSO : ≥ 29 mg/mL (46.96 mM)
• Peso molecolare: 617.600 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 616.211 Da
• Monoisotopic Mass: 616.211 Da
• Topological Polar Surface Area: 34.100 Ų
• Heavy Atom Count: 40
• Formal Charge: 0
• Complexity: 804.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3