Vofopitant dihydrochloride - 10mM in DMSO , CAS No.168266-51-1

CAS: 168266-51-1 Cat. No.: V656221 Formula: C21H25Cl2F3N6O Peso molecolare: 505.36 Numero EC: 800-326-0 PubChem CID: 6918330
Disponibile su ordine
GRADE & PURITY 10mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Germania (EU)
USA*
Price
Qty
1ml
V656221-1ml
Su ordinazione · 8–12 settimane
675,88€
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [ 3 H]SP binding to the NK1 receptor with pK i values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent

IC50& Target:pKi: 9.5 (NK1, rat), 10.6 (NK1, human)

Specifications

Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [ 3 H]SP binding to the NK1 receptor with pK i values of 9.5 and 10.6 in rat and human membranes respectively,
Condizioni di conservazione di stoccaggio
Argon charged,Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Nomi e identificatori
Isomeri SMILES
COC1=C(C=C(C=C1)N2C(=NN=N2)C(F)(F)F)CN[C@H]3CCCN[C@H]3C4=CC=CC=C4.Cl.Cl
CAS alternativo
168266-51-1
PubChem CID
6918330
Termini MeSH
GR205171A;substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)-;Tyr(6)-D-Phe(7)-D-His(9)-substance P (6-11)
Peso molecolare
505.36

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Obiettivi associati (umani)
TACR1 Tclin Substance-P receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Domande frequenti

How should this product be stored?
Store at ?80 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 168266-51-1, the molecular formula is C21H25Cl2F3N6O, and the molecular weight is 505.36 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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