VU 591 hydrochloride - ≥99%(HPLC) , CAS No.1315380-70-1

CAS: 1315380-70-1 Cat. No.: V288854 Formula: C16H12N6O5.HCl Peso molecolare: 404.76 PubChem CID: 90488918
Disponibile su ordine
GRADE & PURITY ≥99%(HPLC)
Synonyms
6-Nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole hydrochloride
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
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Size
Germania (EU)
USA*
Price
Qty
5mg
V288854-5mg
—
6 Disponibile
237,67€
10mg
V288854-10mg
—
5 Disponibile
379,98€
25mg
V288854-25mg
—
3 Disponibile
855,50€
50mg
V288854-50mg
—
3 Disponibile
1.541,02€
100mg
V288854-100mg
—
3 Disponibile
2.774,94€
Enter a quantity for the sizes you want to add.
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Why this grade

≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Product description:

VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride),


Specifications

Sinonimi
6-Nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole hydrochloride
Specifiche e purezza
≥99%(HPLC)
Meccanismi biochimici e fisiologici
Selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50= 300 nM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1
Condizioni di conservazione di stoccaggio
Store at -20°C,Desiccated
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Purezza
≥99%(HPLC)
Nomi e identificatori
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504772608
Sorrisi canonici
C1=CC2=C(C=C1[N+](=O)[O-])NC(=N2)COCC3=NC4=C(N3)C=C(C=C4)[N+](=O)[O-].Cl
IUPAC Name
6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole;hydrochloride
InChIKey
PXLOUHLPDHEXCC-UHFFFAOYSA-N
INCHI
1S/C16H12N6O5.ClH/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16;/h1-6H,7-8H2,(H,17,19)(H,18,20);1H
Isomeri SMILES
C1=CC2=C(C=C1[N+](=O)[O-])NC(=N2)COCC3=NC4=C(N3)C=C(C=C4)[N+](=O)[O-].Cl
PubChem CID
90488918
Peso molecolare
404.76

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseBenzimidazoles
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzimidazoles
Alternative Parents Nitroaromatic compounds  Benzenoids  Imidazoles  Heteroaromatic compounds  Propargyl-type 1,3-dipolar organic compounds  Organic oxoazanium compounds  Dialkyl ethers  Azacyclic compounds  Organonitrogen compounds  Organic zwitterions  Organic oxides  Hydrochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzimidazole - Nitroaromatic compound - Benzenoid - Azole - Imidazole - Heteroaromatic compound - C-nitro compound - Organic nitro compound - Dialkyl ether - Ether - Organic oxoazanium - Azacycle - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic zwitterion - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Hydrochloride - Aromatic heteropolycyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds).
External Descriptors Not available
Struttura 3D
Modello di struttura chimica interattiva





Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDataOggetto
F23061547Certificate of AnalysisMar 18, 2026 V288854
F23061556Certificate of AnalysisMar 18, 2026 V288854
F23061560Certificate of AnalysisMar 18, 2026 V288854
F23061602Certificate of AnalysisMar 18, 2026 V288854
F23061603Certificate of AnalysisMar 18, 2026 V288854
F23061619Certificate of AnalysisMar 18, 2026 V288854
F23061990Certificate of AnalysisMar 18, 2026 V288854
F23061991Certificate of AnalysisMar 18, 2026 V288854
F23062014Certificate of AnalysisMar 18, 2026 V288854
F23062067Certificate of AnalysisMar 18, 2026 V288854
Proprietà chimiche e fisiche
SolubilitàSolvent:DMSO, Max Conc. mg/mL: 36.83, Max Conc. mM: 100
SensibilitàMoisture sensitive
Peso molecolare404.760 g/mol
XLogP3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass404.064 Da
Monoisotopic Mass404.064 Da
Topological Polar Surface Area158.000 Ų
Heavy Atom Count28
Formal Charge0
Complexity520.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Calcolatori di soluzioni
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