WIN 54954 - 10mM in DMSO , CAS No.107355-45-3

CAS: 107355-45-3 Cat. No.: W655912 Formula: C₁₈H₂₀Cl₂N₂O₃ Peso molecolare: 383.27 PubChem CID: 441048

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.

In Vitro

WIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL).\nWIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC 80 of 0.06 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.

Condizioni di conservazione di stoccaggio

Protected from light,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

Isomeri SMILES

CC1=NOC(=C1)CCCCCOC2=C(C=C(C=C2Cl)C3=NCCO3)Cl

PubChem CID

441048

Peso molecolare

383.27