ZL006 - ≥98% , CAS No.1181226-02-7

CAS: 1181226-02-7 Cat. No.: Z412905 Formula: C₁₄H₁₁Cl₂NO₄ Peso molecolare: 328.15 Numero EC: 694-509-0 PubChem CID: 44207238

QUALITÀ & PUREZZA ≥98%

Synonyms

1181226-02-7 | ZL006, >=98% (HPLC) | EC-000.2528 | MS-24906 | 4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-2-hydroxybenzoic acid | HY-100456 | 245DFR6JM5 | SCHEMBL15367533 | BCP32613 | ZL006 | ZL-006 | 4-(3,5-dichloro-2-hydroxy-benzylamino)-2-hydroxybenz

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Information

ZL006 is a potent nNOS/PSD-95 interaction inhibitor, and inhibits NMDA receptor-mediated NO synthesis.

Specifiche

Sinonimi

1181226-02-7 | ZL006, >=98% (HPLC) | EC-000.2528 | MS-24906 | 4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-2-hydroxybenzoic acid | HY-100456 | 245DFR6JM5 | SCHEMBL15367533 | BCP32613 | ZL006 | ZL-006 | 4-(3,5-dichloro-2-hydroxy-benzylamino)-2-hydroxybenz

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

ZL006 is a potent nNOS/PSD-95 interaction inhibitor, and inhibits NMDA receptor-mediated NO synthesis.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

528768571

Sorrisi canonici

C1=CC(=C(C=C1NCC2=C(C(=CC(=C2)Cl)Cl)O)O)C(=O)O

IUPAC Name

4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-2-hydroxybenzoic acid

InChIKey

RTEYSQSXRFVKTJ-UHFFFAOYSA-N

INCHI

1S/C14H11Cl2NO4/c15-8-3-7(13(19)11(16)4-8)6-17-9-1-2-10(14(20)21)12(18)5-9/h1-5,17-19H,6H2,(H,20,21)

Isomeri SMILES

C1=CC(=C(C=C1NCC2=C(C(=CC(=C2)Cl)Cl)O)O)C(=O)O

WGK Germania

3

PubChem CID

44207238

Peso molecolare

328.15

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Phenylmethylamines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Phenylmethylamines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylbenzamines
• Alternative Parents: 4-aminosalicylic acids Aminosalicylic acids Aminobenzoic acids Salicylic acids Benzoic acids m-Aminophenols Aniline and substituted anilines Phenylalkylamines Benzoyl derivatives Benzylamines Dichlorobenzenes O-chlorophenols P-chlorophenols 1-hydroxy-2-unsubstituted benzenoids Secondary alkylarylamines 1-hydroxy-4-unsubstituted benzenoids Aryl chlorides Vinylogous acids Amino acids Carboxylic acids Hydrocarbon derivatives Organic oxides Organochlorides Organooxygen compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Phenylbenzamine - 4-aminosalicylic acid - Aminosalicylic acid - Aminosalicylic acid or derivatives - Aminobenzoic acid - Aminobenzoic acid or derivatives - Hydroxybenzoic acid - Salicylic acid or derivatives - Salicylic acid - Benzoic acid or derivatives - Benzoic acid - M-aminophenol - Aminophenol - Benzoyl - Benzylamine - 1,3-dichlorobenzene - 4-halophenol - 2-halophenol - 2-chlorophenol - 4-chlorophenol - Phenylalkylamine - Aniline or substituted anilines - Aralkylamine - Secondary aliphatic/aromatic amine - Phenol - Chlorobenzene - 1-hydroxy-4-unsubstituted benzenoid - Halobenzene - 1-hydroxy-2-unsubstituted benzenoid - Aryl chloride - Aryl halide - Vinylogous acid - Amino acid - Amino acid or derivatives - Secondary amine - Carboxylic acid - Carboxylic acid derivative - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Amine - Organohalogen compound - Organic oxygen compound - Organochloride - Organic oxide - Organic nitrogen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as phenylbenzamines. These are aromatic compounds consisting of a benzyl group that is N-linked to a benzamine.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)

Discover Target: TOP2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

Escherichia coli (133304 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TOP3A DNA topoisomerase (41 Activities)

Discover Target: TOP3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 328.100 g/mol
• XLogP3: 4.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 327.007 Da
• Monoisotopic Mass: 327.007 Da
• Topological Polar Surface Area: 89.800 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 371.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1