2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine: Key Facts & FAQs

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine is a fluorinated aryloxy tertiary amine used as a versatile building block in medicinal chemistry and organic synthesis research.

Product Name

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine

SKU

D191488

Molecular Formula

C10H13F2NO

Compound Class

Fluorinated aryloxy tertiary amine

Primary Application

Synthetic intermediate and building block in medicinal and organic chemistry

Supplier

Aladdin Scientific (SKU D191488)

What Is 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine?

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine (SKU D191488) is an organic compound consisting of a 3,4-difluorophenoxy aryl ether linked via an ethylene bridge to a dimethylamino group, making it a tertiary amine with a fluorinated aromatic moiety. The presence of two fluorine substituents on the phenyl ring at the 3 and 4 positions confers distinctive electronic properties—such as increased metabolic stability and altered lipophilicity—that are highly valued in pharmaceutical and agrochemical research. The dimethylaminoethyl fragment provides a basic nitrogen centre commonly exploited in drug design and as a handle for further chemical transformations.

Chemical Properties and Structure

The compound features an aryl ether oxygen connecting the difluorophenyl ring to the two-carbon chain, and a tertiary amine at the terminal position. The 3,4-difluoro substitution pattern on the phenoxy ring is known to influence ring electron density, hydrogen-bonding capacity, and the overall polarity of the molecule compared to unsubstituted or mono-fluorinated analogues. As a tertiary amine, the dimethylamino group is readily protonated under acidic conditions, which is relevant for salt formation, solubility adjustment, and receptor interactions. Researchers should confirm the exact molecular weight, melting point, boiling point, and purity specification from the current certificate of analysis (CoA) supplied with SKU D191488, as these values are batch-dependent.

Handling, Storage, and Safety

As with all tertiary amine reagents, standard laboratory precautions should be observed when working with 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine. Use appropriate personal protective equipment (PPE), including nitrile gloves, safety glasses, and a lab coat. Operations that may generate aerosols or vapours should be conducted in a well-ventilated fume hood. The compound should be stored according to the conditions specified on the product label and CoA—typically in a cool, dry location away from incompatible materials such as strong oxidisers and strong acids. Always consult the Safety Data Sheet (SDS) for D191488 prior to use for full hazard, first-aid, and disposal information.

Applications in Research

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine serves primarily as a building block and synthetic intermediate. Fluorinated phenoxy amines of this structural class are frequently employed in the preparation of pharmacologically active molecules, where the fluorine atoms can modulate binding affinity, bioavailability, and metabolic resistance. The dimethylaminoethoxy scaffold is also encountered in the synthesis of ligands for neurotransmitter receptors and in the development of agrochemical candidates. Additionally, the compound may be used as a reference standard or analytical reagent in method development. Specific published applications should be verified in the primary literature; researchers are encouraged to search relevant databases such as SciFinder or Reaxys for up-to-date use cases.

Ordering and Quality Information

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine is available from Aladdin Scientific under SKU D191488. To place an order, visit the Aladdin Scientific website and search by product name or SKU. Bulk quantities, custom packaging, and pricing enquiries can be directed to the Aladdin Scientific sales team. Each lot is supplied with a certificate of analysis confirming identity, purity, and key physicochemical data. For questions regarding availability, lead times, or technical specifications, contact Aladdin Scientific customer support directly.

Frequently asked questions

What is the molecular formula of 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine?

The molecular formula of 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine is C10H13F2NO, reflecting the difluorophenoxy aryl ether and the dimethylaminoethyl chain. Please verify the exact molecular weight and other physicochemical data against the current certificate of analysis for SKU D191488, as specifications are confirmed per batch.

How should 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine be stored?

Store the compound according to the conditions stated on the product label and the Safety Data Sheet provided with SKU D191488—generally in a cool, dry, well-ventilated area, away from strong oxidising agents and strong acids. Keep the container tightly closed when not in use and protect from light if so indicated on the label.

What are the main research applications of this compound?

2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine is primarily used as a synthetic building block and intermediate in medicinal chemistry, where its fluorinated phenoxy amine scaffold can be incorporated into drug candidates to modulate pharmacokinetic and pharmacodynamic properties. It may also find use in agrochemical research, receptor ligand synthesis, and as an analytical reference standard.

Is a Safety Data Sheet (SDS) available for SKU D191488?

Yes, an SDS is available for 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine (SKU D191488) from Aladdin Scientific. You can download it from the product page on the Aladdin Scientific website or contact customer support to request a copy. Always review the SDS before handling the compound.

How can I order 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine from Aladdin Scientific?

You can order SKU D191488 directly through the Aladdin Scientific website by searching the product name or SKU number and adding the desired quantity to your cart. For bulk orders, custom packaging, or additional pricing information, please contact the Aladdin Scientific sales or customer service team.

References

1. Aladdin Scientific product page for 2-(3,4-Difluorophenoxy)-N,N-dimethylethanamine, SKU D191488. Certificate of Analysis and Safety Data Sheet available on request.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.