Catalysts

Under the combined constraints of “aryl/heteroaryl chlorides (Ar–Cl) + low Pd loading + scale-up reproducibility,” the most common source of instability does not necessarily show up as “a complicated mechanism,” but rather as a more straightforward engineering issue: whether the mode ...

The curing of polyurethane (Polyurethane, PU) systems mainly results from the addition reaction between isocyanate groups (—NCO) and hydroxyl groups (—OH), forming urethane bonds.

During the curing of polyurethane (PU) coatings, wood coatings, adhesives, and sealants, the system must achieve a sufficient reaction rate while maintaining a reasonable application time. After a catalyst is added, if the reaction proceeds too rapidly, the mixed material may thicken ...

Under the combined constraints of “aryl/heteroaryl chlorides (Ar–Cl) + low Pd loading + scale-up reproducibility,” the most common source of instability does not necessarily show up as “a complicated mechanism,” but rather as a more straightforward engineering issue: whether the mode ...

Under the combined constraints of “aryl/heteroaryl chlorides (Ar–Cl) + low Pd loading + scale-up reproducibility,” the most common source of instability does not necessarily show up as “a complicated mechanism,” but rather as a more straightforward engineering issue: whether the mode ...

Introduction: Why Can Chiral Phosphoric Acids (CPAs) Evolve from “Small-Molecule Acids” into a General Tool for Asymmetric Synthesis?

Nickel

A highly effective nickel-catalyzed process enables the direct reductive cross-coupling of equimolar quantities of alkyl and aryl halides in the presence of manganese, demonstrating excellent yield, functional group compatibility, and operational simplicity. This transformation bypasses the ...

Professor Karl Anker Jørgensen and his research team have synthesized (R)- and (S)-α,α-bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether compounds, which excel as chiral organocatalysts for the direct and asymmetric α-functionalization process of aldehydes.

Photoredox catalysis has become a powerful synthetic method, which can form Covalent bond under mild reaction conditions through light irradiation.

Hydrogenation is a very common reaction in which H2 can be introduced through double or triple bonds and is widely used in both laboratory and industrial production. This reaction usually requires the presence of metal catalysts in order to carry out, in the presence of such catalysts, it is ...