Protéine kinase C

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  1. Bisindolylmaleimide X hydrochloride (Ro 31-8425)
    CAS: 145317-11-9 Formule: C26H25ClN4O2 Poids moléculaire: 460.96
    ◐ .Sur commande · 8–12 semaines Article #: B275168
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    Nom IUPAC
    3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione;hydrochloride
    SMILES
    CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN.Cl
    InChIKey
    IMBOYWXMTUUYGZ-UHFFFAOYSA-N
    InChI
    1S/C26H24N4O2.ClH/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30;/h2-9,14-15H,10-13,27H2,1Hshow more
    Synonymes
    3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dionehydrochloride
  2. Bisindolylmaleimide III
    CAS: 137592-43-9 Formule: C23H20N4O2 Poids moléculaire: 384.43
    ● En stock — États-Unis Article #: B276080
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    Nom IUPAC
    3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
    SMILES
    C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN
    InChIKey
    APYXQTXFRIDSGE-UHFFFAOYSA-N
    InChI
    1S/C23H20N4O2/c24-10-5-11-27-13-17(15-7-2-4-9-19(15)27)21-20(22(28)26-23(21)29)16-12-25-18-8-3-1-6-14(16)18/h1-4,6-9,12-13,25H,5,10-11,24H2,(H,26,28,2show more
    Synonymes
    3-[1-(3-Aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
  3. N-octanoyl-D-erythro-sphingosine
    CAS: 74713-59-0 Formule: C26H51NO3 Poids moléculaire: 425.688
    ● En stock — États-Unis Article #: N130616
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    Nom IUPAC
    N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
    SMILES
    CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
    InChIKey
    APDLCSPGWPLYEQ-WRBRXSDHSA-N
    InChI
    1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21show more
    Synonymes
    BSPBio_001569 | HMS1361O11 | N-octanoylsphing-4-enine | SCHEMBL14020687 | DTXSID701318293 | SR-01000946565 | N-Octano...
  4. N-octanoyl-D-erythro-sphinganine
    CAS: 145774-33-0 Formule: C26H53NO3 Poids moléculaire: 427.7
    ◐ .Sur commande · 8–12 semaines Article #: N130688
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    Nom IUPAC
    N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octanamide
    SMILES
    CCCCCCCCCCCCCCCC(C(CO)NC(=O)CCCCCCC)O
    InChIKey
    LGOFBZUQIUVJFS-LOSJGSFVSA-N
    InChI
    1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1
    Synonymes
    EC 214-269-9 | N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octanamide | C8 Dihydroceramide [N-Octanoylsphinganine] | KBioS...
  5. Bisindolylmaleimide II
    CAS: 137592-45-1 Formule: C27H26N4O2 Poids moléculaire: 438.52
    ◐ .Sur commande · 8–12 semaines Article #: B276515
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    Nom IUPAC
    3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
    SMILES
    CN1CCCC1CCN2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
    InChIKey
    LBFDERUQORUFIN-UHFFFAOYSA-N
    InChI
    1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-show more
    Synonymes
    Bisindolyl deriv. 22 | 2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide | SCHEMBL7978085...
  6. Bisindolylmaleimide IV, Inhibitor of protein kinase C beta
    CAS: 119139-23-0 Formule: C20H13N3O2 Poids moléculaire: 327.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(TLC)
    ● En stock — États-Unis Article #: B166335
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    Nom IUPAC
    3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
    SMILES
    C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
    InChIKey
    DQYBRTASHMYDJG-UHFFFAOYSA-N
    InChI
    1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
    Synonymes
    CCG-206739 | HMS3229C03 | RO-316233 | Ro-31-6233 | DTXSID30152324 | FT-0694431 | GTPL5937 | HMS3401J13 | MBK3OO5K8T |...
  7. Bisindolylmaleimide VIII acetate
    CAS: 138516-31-1 Formule: C24H22N4O2.CH3CO2H Poids moléculaire: 458.51
    ● En stock — États-Unis Article #: B274850
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    Nom IUPAC
    acetic acid;3-[1-(3-aminopropyl)indol-3-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
    SMILES
    CC(=O)O.CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN
    InChIKey
    VEOXVBTXROWDAH-UHFFFAOYSA-N
    InChI
    1S/C24H22N4O2.C2H4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20;1-2(3)4/h2-5,7-10,13-14H,6,11-12show more
    Synonymes
    HMS3648M22 | Z2037279705 | Bis VIII acetate | Bis VIII acetateRo 31-7549 acetate | DTXSID50432099 | 1-(p-Fluorophenyl...
  8. LY-333531 hydrochloride
    CAS: 169939-93-9 Formule: C28H28N4O3 · HCl Poids moléculaire: 505.01
    ● En stock — États-Unis Article #: L274839
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    Nom IUPAC
    (18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-show more
    SMILES
    CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
    InChIKey
    NYQIEYDJYFVLPO-FERBBOLQSA-N
    InChI
    1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-show more
    Synonymes
    LY333531 HCl | (9S)-9-[(DiMethylaMino)Methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-DiMethenodibenzo[e,k]pyrrolo[3,4...
  9. K-252c
    CAS: 85753-43-1 Numéro CE: 632-917-2 Formule: C20H13N3O Poids moléculaire: 311.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Sur commande · 8–12 semaines Article #: K276286
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    Nom IUPAC
    3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-12-one
    SMILES
    C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5
    InChIKey
    MEXUTNIFSHFQRG-UHFFFAOYSA-N
    InChI
    1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8,22-23H,9H2,(H,21,24)
    Synonymes
    BRD-K93879806-001-01-4 | SCHEMBL5440281 | 3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa...
  10. Mitoxantrone, Inhibitor of DNA topoisomerase II alpha
    CAS: 65271-80-9 Numéro CE: 833-758-3 Formule: C22H28N4O6 Poids moléculaire: 444.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — États-Unis Article #: M339846
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    Nom IUPAC
    1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
    SMILES
    C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO
    InChIKey
    KKZJGLLVHKMTCM-UHFFFAOYSA-N
    InChI
    1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
    Synonymes
    L01DB07 | 5,8-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)-1,4-dihydroxyanthraquinone | HMS2090D05 | 1,4-dihydroxy-5,8-...
  11. Ro 32-0432 hydrochloride
    CAS: 1781828-85-0 PubChem CID: 70346044 Formule: C28H28N4O2.HCl Poids moléculaire: 489.01
    ◐ .Sur commande · 8–12 semaines Article #: R288387
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    Nom IUPAC
    3-[(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione;hydrochloride
    SMILES
    CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN(C)C.Cl
    InChIKey
    HSPRASOZRZDELU-LMOVPXPDSA-N
    InChI
    1S/C28H28N4O2.ClH/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21;/h4-11,16-17H,12-15Hshow more
    Synonymes
    3-[(8S)-8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2...
  12. 1-Stearoyl-2-arachidonoyl-sn-glycerol, Activator of TRPC6
    CAS: 65914-84-3 PubChem CID: 6438587 Formule: C41H72O5 Poids moléculaire: 645.01
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% 25mg/ml in methyl acetate
    ◐ .Sur commande · 8–12 semaines Article #: S347974
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    Nom IUPAC
    [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
    SMILES
    CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
    InChIKey
    NSXLMTYRMFVYNT-IUJDHQGTSA-N
    InChI
    1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,1show more
    Synonymes
    DG(18:0/20:4(omega-6)/0:0) | DG(18:0/20:4omega6) | (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icos...
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Foire aux questions

What can I find under PKC?
This listing collects compounds associated with PKC within our Epigenetics area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for PKC?
Consider the reported potency of each PKC compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for PKC compounds?
Each PKC product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search PKC compounds by activity or structure?
Yes. Filter the PKC listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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