Motesanib - Moligand™, 10mM in DMSO , Platelet-derived growth factor receptor inhibitor, CAS No.453562-69-1, Platelet-derived growth factor receptor inhibitor
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SKU
M424063
Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
An inhibitor of Flk-1, Flt-4, PDGFR-β and c-Kit.
Plus d’information
| CAS | 453562-69-1 |
|---|---|
| Concentration | 10mM in DMSO |
| Synonymes | N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | NSC800801 | NSC-800801 | HMS3244B09 | HY-10228 | N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-((pyridin-4-ylmethyl)amino)pyridine-3-carboxamide | SCHEMBL2416976 | D |
| Spécifications et pureté | Moligand™, 10mM in DMSO |
| Conditions de stockage de stockage | Store at -80°C |
| Expédié en | Dry ice packs + Cold packs |
| Product Description | Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. |
| Numéro CE | 113-839-3 |
| PubChem CID | 11667893 |
| Formule moléculaire | C22H23N5O |
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