CD8 alpha Mouse mAb (FITC) - 一次抗体, specific to CD8 alpha

Cat. No.: Ab190485

GRADE & PURITY Validated, ExactAb™, Ex:498nm, Em:517nm, 5 μL/test

Application

Flow Cytometry

Host species

マウス

Reactive species

人間

Isotype

Mouse IgG2a

Clone Number

OKT-8

Conjugation

FITC

概要

Mouse anti Human CD8 alpha Antibody, Monoclonal (OKT-8), could be used for Flow, in vivo CD8+ T cell depletion in humanized mice and so on.

Specifications

Product Name

CD8 alpha Mouse mAb (FITC) - 一次抗体, specific to CD8 alpha

同義語

CD8 | Leu2 | IMD116 | CD8alpha | CD_antigen: CD8a | CD8 antigen, alpha polypeptide (p32) | FITC Anti-Human CD8a Antibody[OKT-8] | FITC Anti-Human CD8a (OKT8) | FITC Mouse Anti-Human CD8 | CD8a Monoclonal Antibody (OKT-8), FITC | FITC anti-human CD8a Antib

仕様と純度

ExactAb™, Validated, Ex:498nm, Em:517nm, 5 μL/test

生化学的・生理学的メカニズム

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

宿主種

マウス

特異性

CD8 alpha

免疫原

Human CD8α

ポジティブコントロール

Flow: Human peripheral blood lymphocytes

活用

FITC

励起波長(nm)

Blue Laser(488nm)

発光波長(nm)

517nm

Ex/Em(nm)

Ex:498nm;Em:517nm

等級

Em:517nm, Ex:498nm, ExactAb™, Validated

ライトチェーン・タイプ

kappa

精製方法

Protein G purified

集中

5 μL/test

保管と配送

保管条件

Store at 2-8°C,Protected from light,Do not freeze

入荷

Wet ice,Do not freeze

安定性と保管

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

画像

Flow Cytometry: CD8 alpha Mouse mAb (FITC) (Ab190485)

CD8 alpha Mouse mAb (FITC) (Ab190485) - Flow Cytometry
Flow cytometry analysis of CD8 alpha expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with CD8 alpha Mouse mAb (FITC) (Ab190485) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (FITC) (Ab180307).

Flow Cytometry: CD8 alpha Mouse mAb (FITC) (Ab190485)

CD8 alpha Mouse mAb (FITC) (Ab190485) - Flow Cytometry
Flow cytometry analysis of CD8 alpha expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with CD8 alpha Mouse mAb (FITC) (Ab190485) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (FITC) (Ab180307). Black - Unlabelled control, cells without incubation with primary antibody.

適用＃テキヨウ＃

• 適用＃テキヨウ＃: Dilution info
• Flow Cytometry:

  5 μL/test, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood ;

関連ターゲット（人間）

CD8A Tbio T-cell surface glycoprotein CD8 alpha chain (0 Activities)

Discover Target: CD8A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)