How do I determine if a compound is cell-permeable?
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How do I determine if a compound is cell-permeable?
·Reviewed·Published ·Updated ·8 min read
How do I determine if a compound is cell-permeable？
There is no easy way of predicting if a product will be cell-permeable. Generally charged molecules are not cell-permeable. However, modified phosphorylated compounds, such as mono- and dibutyryl cAMP, are cell-permeable. High molecular weight peptides are generally not cell-permeable under normal conditions.
Da — when not otherwise indicated, molecular weight units are daltons. Mw — weight-average molecular weight. Mn — number-average molecular weight.
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Aladdin Scientific. "How do I determine if a compound is cell-permeable?" Aladdin Knowledge Base, updated Jul 27, 2023. https://www.aladdinsci.com/us_en/faqs/aladdin-cell-permeable-en.html
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