Articles by tag "C-H Functionalization"

1. [OxB]₂ Handling & Application Guide: Oxazaborolidinone Dimer Diboron
   posted this at 2026/10/15

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   oxazaborolidinone dimer diboron ([OxB]₂) is a bench-stable, electrophilic diboron reagent derived from the cyclic ester of 2-aminoethanol and a boronic acid motif, designed to enable mild and selective 1,2-diboration and borylation reactions that are difficult to achieve with conventional ...
2. 2,3-Dichloro-5,6-Dicyanobenzoquinone, DDQ
   posted this at 2024/12/10

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   Product Manager：Nick WildeDDQ (2,3-dichloro-5,6-dicyanobenzoquinone), which exhibits stronger oxidizing properties than 1,4-benzoquinone, serves as a reagent in oxidative coupling and cyclization reactions, as well as in the dehydrogenation of hydroaromatic compounds.Recent ...
3. White Catalyst
   posted this at 2024/11/10

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   Product Manager：Nick WildeIntroductionThe "White catalyst" (B488782), developed by Professor M. Christina White and her team at the University of Illinois-Urbana, has proven to be an outstanding catalyst for the functionalization of allylic carbon centers.Figure 1.White Catalyst (B488782)The ...
4. Electrochemical Allylic C-H Oxidation with N-Hydroxytetrachlorophthalimide (TCNHPI)
   posted this at 2024/10/31

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   IntroductionProfessor Phil Baran and his team have created a new reagent called N-Hydroxytetrachlorophthalimide (H401609), which offers a cost-effective, scalable, and safe alternative for commonly used chemical transformations such as allylic oxidations, as well as Negishi and Suzuki-Miyaura ...
5. Diversinates™: Any-Stage Functionalization of (Hetero)aromatic Scaffolds
   posted this at 2024/09/25

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   Product Manager：Nick WildeIntroductionThe core of the chemical industry revolves around the synthesis of heteroaromatic and aromatic compounds. Given the escalating demand for novel chemical entities amidst dwindling resources and tight timelines imposed on research projects, there is a ...
6. MCAT-53™ Catalyst for Ruthenium Formation
   posted this at 2024/09/24

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   Product Manager：Nick Wilde​MCAT-53™, a novel ruthenium catalyst, simplifies C-H activated C-C coupling in water by eliminating extra steps and avoiding solvents like NMP. Chicago Discovery Solutions has pioneered MCAT-53™, a recyclable and ligand-free ruthenium catalyst that enhances ...
7. Jørgensen’s Organocatalysts
   posted this at 2024/08/20

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   Product Manager：Nick WildeIntroductionProfessor Karl Anker Jørgensen and his research team have synthesized (R)- and (S)-α,α-bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether compounds, which excel as chiral organocatalysts for the direct and asymmetric ...
8. C–H Amination
   posted this at 2024/07/07

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   Product Manager：Nick WildeThe Du Bois group at Stanford University has achieved significant advancements in Rh-catalyzed C–H amination through oxidative cyclization of carbamate, sulfamate, sulfamide, urea, and guanidine substrates. This methodology produces 1,2- and 1,3-heteroatom motifs ...
9. N-Bromosuccinimide (NBS)
   posted this at 2024/05/22

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   Product Manager：Nick WildeN-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by ...