MSOP - Moligand™ , Antagonist of mGlu 2 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor, CAS No.66515-29-5, Antagonist of mGlu 2 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor

CAS: 66515-29-5 Cat. No.: M275068 分子式: C₄H₁₀NO₆P 分子量: 199.1 EC番号: 809-692-6

グレード＆純度 Moligand™

Synonyms

(RS)-?-Methylserine-O-phosphate | 2-AMINO-2-METHYL-3-(PHOSPHONOOXY)PROPANOIC ACID | DTXSID40398271 | Q27074406 | alpha-MSOP | alpha-methylserine-O-phosphate | HY-101226 | GTPL1398 | SR-01000597443 | SR-01000597443-1 | MSOP | NCGC00024799-02 | (RS)-ALPHA-M

Storage

Room temperature

Shipped In

Normal

概要

Store at Room Temperature. The product can be stored for up to 12 months.

仕様

同義語

(RS)-?-Methylserine-O-phosphate | 2-AMINO-2-METHYL-3-(PHOSPHONOOXY)PROPANOIC ACID | DTXSID40398271 | Q27074406 | alpha-MSOP | alpha-methylserine-O-phosphate | HY-101226 | GTPL1398 | SR-01000597443 | SR-01000597443-1 | MSOP | NCGC00024799-02 | (RS)-ALPHA-M

仕様と純度

Moligand™

生化学的・生理学的メカニズム

Potent, selective group III metabotropic glutamate receptor antagonist.

保管条件

Room temperature

入荷

Normal

等級

Moligand™

アクションタイプ

ANTAGONIST

作用メカニズム

Antagonist of mGlu 2 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

名前と識別子

カノニカル・スマイル

CC(COP(=O)(O)O)(C(=O)O)N

IUPAC Name

2-amino-2-methyl-3-phosphonooxypropanoic acid

InChIKey

GSFCOAGADOGIGE-UHFFFAOYSA-N

INCHI

1S/C4H10NO6P/c1-4(5,3(6)7)2-11-12(8,9)10/h2,5H2,1H3,(H,6,7)(H2,8,9,10)

異性体SMILES

CC(COP(=O)(O)O)(C(=O)O)N

代替CAS番号

66515-29-5

MeSH用語

(RS)-alpha-methylserine-O-phosphate;alpha-MSOP;methylserine phosphate;MSOP

分子量

199.1

Reaxy-Rn

8684553

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8684553&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 分類 Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 分類: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acids
• Alternative Parents: Phosphoethanolamines Monoalkyl phosphates Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid - Phosphoethanolamine - Monoalkyl phosphate - Organic phosphoric acid derivative - Alkyl phosphate - Phosphoric acid ester - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Amine - Aliphatic acyclic compound
• 説明: This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

GRM2 Tchem Metabotropic glutamate receptor 2 (1 Activities)

Discover Target: GRM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM7 Tchem Metabotropic glutamate receptor 7 (1 Activities)

Discover Target: GRM7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM8 Tchem Metabotropic glutamate receptor 8 (1 Activities)

Discover Target: GRM8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM6 Tchem Metabotropic glutamate receptor 6 (1 Activities)

Discover Target: GRM6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

関連ターゲット（非人間）

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 溶解度: Soluble in water to 100 mM
• 分子量: 199.100 g/mol
• XLogP3: -5.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 199.025 Da
• Monoisotopic Mass: 199.025 Da
• Topological Polar Surface Area: 130.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 224.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 66515-29-5, the molecular formula is C4H10NO6P, and the molecular weight is 199.1 g/mol. InChIKey GSFCOAGADOGIGE-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.