Name: Nicotinamide - for cell culture, suitable for insect cell culture, ≥99.5%(HPLC), used for Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells , esophageal squamous cell carcinomas(ESCC) pancreatic cancer organoi
Brand: Aladdin Scientific
SKU: N108087
Availability: InStock

概要仕様名前と識別子ドキュメント詳細データ Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質よくある質問と記事 Citations of This Product ソリューション計算機レビュー

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このグレードを選ぶ理由

for cell culture, suitable for insect cell culture, ≥99.5%(HPLC) 昆虫細胞培養に適している,細胞培養用ベースライン干渉を最小限に抑える必要がある、感度の高いクロマトグラフィーおよび分析ワークフロー向け。

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保管・配送

Room temperature,Desiccated Normal に出荷。正確な仕様については、ロット固有の COA をご確認ください。

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品質書類

SDS、COA、データシート、仕様書をダウンロードできます。ロット固有の COA はロット番号検索で入手可能です。

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文献的裏付け

クロマトグラフィー、有機合成、クロスカップリング反応に関する 85 件の査読済み論文で引用されています。

概要

Nicotinamide is a NAD+ and NADP+ coenzyme precursor. Nicotinamide is an antiinflammatory agent and a PARP-1 enzyme inhibitor.
An NAD+ and NADP+ coenzyme precursor

仕様

同義語

仕様と純度

for cell culture, suitable for insect cell culture, ≥99.5%(HPLC)

生化学的・生理学的メカニズム

Amide form of vitamin B 3 . Plasma membrane and blood-brain barrier permeable. Precursor for β-nicotinamide adenine dinucleotide (NAD + ). Essential for the synthesis of NAD + phosphate (NADP + ). Essential for energy metabolism, normal physiology and dis

申し込み

Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells , esophageal squamous cell carcinomas(ESCC) pancreatic cancer organoids and pancreatic progenitor induction.

保管条件

Room temperature,Desiccated

入荷

Normal

等級

昆虫細胞培養に適している, 細胞培養用

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥99.5%(HPLC)

名前と識別子

パブケム・シド

508814626

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/508814626

カノニカル・スマイル

C1=CC(=CN=C1)C(=O)N

IUPAC Name

pyridine-3-carboxamide

InChIKey

DFPAKSUCGFBDDF-UHFFFAOYSA-N

INCHI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

異性体SMILES

C1=CC(=CN=C1)C(=O)N

WGKドイツ

RTECS

QS3675000

分子量

122.12

Beilstein

383619

Reaxy-Rn

383619

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=383619&ln=

ドキュメント

📋 安全データシート（SDS）

危険性、取扱い、保管、および規制遵守を網羅した包括的な文書。

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✅ 分析証明書（COA）

ロット固有の品質データ。ロット番号を入力して、正確な COA を取得してください。

COA を検索 →

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製品仕様と用途のクイックリファレンス概要。

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🔬 仕様書

このグレードの完全な品質特性と合格基準。

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詳細データ

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - 分類 Pyridines and derivatives
    - Subclass Pyridinecarboxylic acids and derivatives
      - Level5 Pyridinecarboxamides
        Level6 Nicotinamides

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
分類	Pyridines and derivatives
Subclass	Pyridinecarboxylic acids and derivatives
Intermediate Tree Nodes	Pyridinecarboxamides
Direct Parent	Nicotinamides
Alternative Parents	Heteroaromatic compounds Primary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Nicotinamide - Heteroaromatic compound - Primary carboxylic acid amide - Carboxamide group - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
説明	This compound belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group.
External Descriptors	a vitamin - an aliphatic amide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

関連ターゲット（非人間）

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

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Mc4r Melanocortin receptor 4 (1205 Activities)

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Ltc4s Leukotriene C4 synthase (1 Activities)

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Sigmar1 Sigma opioid receptor (160 Activities)

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Npy1r Neuropeptide Y receptor type 1 (8 Activities)

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Cckar Cholecystokinin A receptor (90 Activities)

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Nos2 Nitric oxide synthase, inducible (3573 Activities)

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Mapk1 MAP kinase ERK2 (650 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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Faah Anandamide amidohydrolase (3907 Activities)

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Mmp9 Matrix metalloproteinase 9 (38 Activities)

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SIR2 NAD-dependent histone deacetylase SIR2 (218 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Leishmania infantum (5912 Activities)

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Plasmodium falciparum (966862 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Leishmania donovani (89745 Activities)

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Trypanosoma cruzi (99888 Activities)

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Toxoplasma gondii (4585 Activities)

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Rattus norvegicus (775804 Activities)

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Trypanosoma brucei rhodesiense (7991 Activities)

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RAW264.7 (28094 Activities)

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panE Ketopantoate reductase (28 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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HST2 NAD-dependent deacetylase HST2 (97 Activities)

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Plasma (328 Activities)

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SIR2RP1 Putative silent information regulator 2 (21 Activities)

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cobB NAD-dependent protein deacetylase (1 Activities)

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Glra2 Glycine receptor (1745 Activities)

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SARS-CoV-2 (38078 Activities)

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Sarm1 NAD(+) hydrolase SARM1 (23 Activities)

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作用メカニズム

証明書（CoA、COO、BSE/TSEと分析図）

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot Number	Certificate Type	日付	商品
E2622148	Certificate of Analysis	Jun 01, 2026	N108087
E2622149	Certificate of Analysis	Jun 01, 2026	N108087
K2504001	Certificate of Analysis	Nov 08, 2025	N108087
K2504012	Certificate of Analysis	Nov 08, 2025	N108087
B2525348	Certificate of Analysis	Dec 14, 2024	N108087
B2525349	Certificate of Analysis	Dec 14, 2024	N108087
B2309199	Certificate of Analysis	Jun 25, 2022	N108087
G2222535	Certificate of Analysis	Jun 25, 2022	N108087
G2222642	Certificate of Analysis	Jun 25, 2022	N108087
H2317080	Certificate of Analysis	Jun 25, 2022	N108087
K2429108	Certificate of Analysis	Jun 25, 2022	N108087
K2503071	Certificate of Analysis	Jun 25, 2022	N108087
L2307178	Certificate of Analysis	Jun 25, 2022	N108087

化学的性質と物理的性質

溶解度	Soluble in water (1000 g/l) at 20 °C, ethanol (100 mM), glycerol (1 g/10ml), DMSO (100 mM), methanol, butanol, chloroform, and ether (Slightly).
感度	light sensitive
引火点（°F）	302 °F
引火点（°C）	150 °C
融点（°C）	128-131°C
分子量	122.120 g/mol
XLogP3	-0.400
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	122.048 Da
Monoisotopic Mass	122.048 Da
Topological Polar Surface Area	56.000 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	114.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Cell proliferation3

Cell viability4

Cytotoxicity screening5

Drug / compound screening13

Organic synthesis — reaction medium32

Extraction & workup solvent24

Industrial & non-pharma application2

Other applications34

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Controlled-release & nanoparticle carrier5

Crystallization & recrystallization13

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Film coating1

IC50 determination1

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当社のグレード選定ガイドでは、カタログ内のすべてのバリエーションについて、純度、安定剤の状態、用途への適合性を網羅しています。

for Cell culture グレードガイドを見る → Suitable for insect cell culture グレードガイドを見る →

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Nicotinamide - for cell culture, suitable for insect cell culture, ≥99.5%(HPLC), used for Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells , esophageal squamous cell carcinomas(ESCC) pancreatic cancer organoi

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Nicotinamide - for cell culture, suitable for insect cell culture, ≥99.5%(HPLC), used for Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells , esophageal squamous cell carcinomas(ESCC) pancreatic cancer organoi

保管・配送

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概要

仕様

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