2′,6-Dihydroxyflavone - ≥97% , CAS No.92439-20-8

CAS: 92439-20-8 Cat. No.: D337677 Fórmula: C₁₅H₁₀O₄ Peso molecular: 254.24 Número CE: 635-645-2

GRADE & PURITY ≥97%

Synonyms

6,2'-Dihydroxyflavone | 2,6-dihydroxyflavone | 6-hydroxy-2-(2-hydroxyphenyl)chromen-4-one

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.

Specifications

Sinónimos

6,2'-Dihydroxyflavone | 2,6-dihydroxyflavone | 6-hydroxy-2-(2-hydroxyphenyl)chromen-4-one

Especificações e pureza

≥97%

Mecanismos bioquímicos e fisiológicos

6,2′-Dihydroxyflavone is a partial inverse agonist at GABAA receptors with α-subunit selectivity.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

ANTAGONIST

Pureza

≥97%

Nomes e identificadores

Pubchem Sid

528755038

Sorrisos canónicos

C1=CC=C(C(=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O)O

IUPAC Name

6-hydroxy-2-(2-hydroxyphenyl)chromen-4-one

InChIKey

YCGXYGWBHFKQHY-UHFFFAOYSA-N

INCHI

1S/C15H10O4/c16-9-5-6-14-11(7-9)13(18)8-15(19-14)10-3-1-2-4-12(10)17/h1-8,16-17H

SMILES isoméricas

C1=CC=C(C(=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O)O

Peso molecular

254.24

Reaxy-Rn

233423

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=233423&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Classe Flavonoids
      • Subclass Flavones

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Classe: Flavonoids
• Subclass: Flavones
• Intermediate Tree Nodes: Not available
• Direct Parent: Flavones
• Alternative Parents: 6-hydroxyflavonoids Chromones Pyranones and derivatives 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Heteroaromatic compounds Oxacyclic compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-hydroxyflavonoid - Flavone - Hydroxyflavonoid - Chromone - Benzopyran - 1-benzopyran - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Monocyclic benzene moiety - Benzenoid - Pyran - Heteroaromatic compound - Oxacycle - Organoheterocyclic compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as flavones. These are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 254.240 g/mol
• XLogP3: 3.300
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 254.058 Da
• Monoisotopic Mass: 254.058 Da
• Topological Polar Surface Area: 66.800 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 390.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1