By Signaling Pathways

Explore pathway-focused tool compounds to study and modulate key signaling cascades. Browse small molecules grouped by signaling pathway to support mechanism studies, phenotypic assays, and target validation, with clear identifiers for fast searching.

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

102,749 products

Browse pathway-oriented compounds relevant to anti-infection research, host–pathogen studies, and antimicrobial screening. Use this page to identify molecules associated with infection-related biology, cellular defense, and therapeutic discovery workflows.

Browse pathway-focused compounds for autophagy research, lysosomal biology, and cellular stress-response studies. Use this page to compare molecules relevant to autophagy flux, organelle turnover, and mechanism-driven assay work.

Explore pathway-focused compounds for epigenetics research, including tools relevant to chromatin regulation and transcriptional control. Use this page to compare molecules used in target validation, mechanism studies, and cell-state modulation workflows.

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

Explore pathway-focused small molecules tied to metabolic enzyme and protease biology for mechanism studies, screening, and target validation. This page helps you review compounds relevant to catalytic pathways, substrate processing, and protease-driven cellular responses.

Find small molecules associated with PI3K/Akt/mTOR signaling for growth control, metabolism research, and oncology workflows. This category helps organize pathway modulators used in screening, target validation, and signal-transduction studies.

Find small molecules associated with stem cell and Wnt signaling for differentiation studies, cell-fate control, and pathway research. This category helps organize compounds used in developmental biology, regenerative research, and signaling modulation.

Browse small molecules linked to cell cycle control and DNA damage pathways for oncology research, checkpoint studies, and assay development. Use this category to compare compounds relevant to proliferation control, repair mechanisms, and stress-response signaling.

Browse small molecules mapped to GPCR and G protein signaling for receptor biology, pathway interrogation, and assay development. Use this page to compare modulators that help probe upstream signaling, second messengers, and receptor-driven responses.

Explore compounds linked to the MAPK/ERK pathway for signal-transduction research, proliferation studies, and response-pathway analysis. Use this page to compare modulators relevant to kinase cascades and downstream cellular signaling outputs.

Explore small molecules connected to neuronal signaling for neurotransmission studies, neuropharmacology, and pathway research. This page helps organize compounds used to interrogate receptors, signaling nodes, and functional responses in neurobiology workflows.

Find small molecules associated with TGF-beta/Smad signaling for fibrosis research, differentiation studies, and pathway crosstalk analysis. Use this page to explore compounds relevant to growth control, developmental signaling, and translational biology.

Browse small molecules connected to apoptosis pathways for cell-death studies, stress-response research, and phenotypic screening. This category helps you compare compounds relevant to survival signaling, programmed cell death, and mechanism-based assays.

Find pathway-focused compounds for cytoskeleton research, including tools used in motility, trafficking, and cell-shape studies. Use this page to explore molecules relevant to structural dynamics and cytoskeleton-driven cellular behavior.

Find pathway-focused compounds for immunology and inflammation research, including tools relevant to cytokine signaling and immune regulation. This category supports screening and mechanism work in inflammatory pathways, immune-cell responses, and translational biology.

Find pathway-focused compounds related to membrane transporters and ion channels for transport biology, electrophysiology, and screening studies. This page helps you review modulators relevant to ion flow, substrate transport, and membrane-associated signaling.

NF-κB

2,563

Browse pathway-focused small molecules for NF-κB research, inflammation studies, and transcriptional response assays. This category supports work on immune signaling, stress pathways, and mechanism-based screening around a central regulatory node.

Explore small molecules mapped to protein tyrosine kinase and receptor tyrosine kinase signaling for growth-factor biology and oncology research. This category supports focused screening and pathway studies around phosphorylation-driven signaling networks.

Explore small molecules linked to vitamin D–related and nuclear receptor signaling for endocrine biology, receptor studies, and transcription research. This category helps organize modulators tied to ligand-regulated pathways and downstream gene-control mechanisms.

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  1. (R,S)-3,5-DHPG
    CAS: 19641-83-9 Formula: C8H9NO4 Molecular Weight: 183.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: D274657
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    Synonyms
    (R,S)-3,5-Dihydroxyphenylglycine
  2. Benperidol(Anquil), Dopamine D2 receptor antagonist
    CAS: 2062-84-2 EC Number: 218-172-2 Formula: C22H24FN3O2 Molecular Weight: 381.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    Out of Stock Item #: B607988
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    IUPAC Name
    3-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1H-benzimidazol-2-one
    SMILES
    C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F
    InChIKey
    FEBOTPHFXYHVPL-UHFFFAOYSA-N
    InChI
    1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)
    Synonyms
    3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one | 97O6X78C53 | BENPERIDOL [WHO-DD] | CAS_20...
  3. GSK2850163
    CAS: 2121989-91-9 PubChem CID: 73291790 Formula: C24H29Cl2N3O Molecular Weight: 446.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: G650135
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    IUPAC Name
    (5R)-2-[(3,4-dichlorophenyl)methyl]-N-[(4-methylphenyl)methyl]-2,7-diazaspiro[4.5]decane-7-carboxamide
    SMILES
    CC1=CC=C(C=C1)CNC(=O)N2CCCC3(C2)CCN(C3)CC4=CC(=C(C=C4)Cl)Cl
    InChIKey
    YFDASBFQKMHSSJ-XMMPIXPASA-N
    InChI
    1S/C24H29Cl2N3O/c1-18-3-5-19(6-4-18)14-27-23(30)29-11-2-9-24(17-29)10-12-28(16-24)15-20-7-8-21(25)22(26)13-20/h3-8,13H,2,9-12,14-17H2,1H3,(H,27,30)/t2show more
    Synonyms
    (R)-2-(3,4-Dichlorobenzyl)-N-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Gsk2850163
  4. Cell Cycle and Apoptosis Analysis Kit
    Liquid Sterile-filtered ? Sterile-filtered — passed through a 0.2µm filter to remove microorganisms. Use as a ready aseptic solution for culture and sensitive applications. BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. Ready-to-use ? Ready-to-use — supplied pre-formulated at working concentration, no prep needed. Use to save time and reduce pipetting/dilution errors. Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. for Fluorescence analysis ? Fluorescence-analysis grade — very low fluorescent impurities for clean spectra. Use in fluorescence assays where background interferes. for Microscopy ? Microscopy grade — reagents/stains suited to sample prep and imaging. Use in microscopy where clarity and low background are needed. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. for DNA and RNA applications ? For nucleic-acid (DNA & RNA) applications — nuclease-controlled across both. Use in workflows handling DNA and RNA together where degradation is a risk. Suitable for Immunofluorescence(IF) ? IF grade — validated for immunofluorescence with low background staining. Use to localize targets in cells/tissue by fluorescence microscopy.
    Out of Stock Item #: P1373478
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  5. 4-chloro-α-Cyanocinnamic Acid (Cl-CCA)
    CAS: 20374-46-3 EC Number: 830-876-7 PubChem CID: 2363776 Formula: C10H6ClNO2 Molecular Weight: 207.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: C699766
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    IUPAC Name
    (E)-3-(4-chlorophenyl)-2-cyanoprop-2-enoic acid
    SMILES
    C1=CC(=CC=C1C=C(C#N)C(=O)O)Cl
    InChIKey
    MXCRRKYUQNHWLJ-VMPITWQZSA-N
    InChI
    1S/C10H6ClNO2/c11-9-3-1-7(2-4-9)5-8(6-12)10(13)14/h1-5H,(H,13,14)/b8-5+
    Synonyms
    3-(4-Chlorophenyl)-2-cyanoacrylic acid | (E)-3-(4-Chlorophenyl)-2-Cyanoacrylic Acid | (E)-3-(4-Chlorophenyl)-2-Cyano-...
  6. OBAA
    CAS: 134531-42-3 Formula: C28H44O3 Molecular Weight: 428.65
    Out of Stock Item #: O335801
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    IUPAC Name
    4-(4-octadecylphenyl)-4-oxobut-2-enoic acid
    SMILES
    CCCCCCCCCCCCCCCCCCC1=CC=C(C=C1)C(=O)C=CC(=O)O
    InChIKey
    ZBESASFHIWDSCJ-UHFFFAOYSA-N
    InChI
    1S/C28H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-19-21-26(22-20-25)27(29)23-24-28(30)31/h19-24H,2-18H2,1H3,(H,30,31)
    Synonyms
    Bio1_000952 | HMS3266B09 | Q27164591 | KBio2_005460 | KBio2_000324 | KBioGR_000324 | 4-(4-Octadecylphenyl)-4-oxo-2-bu...
  7. BQ-123, Antagonist of ET A receptor
    CAS: 136553-81-6 Formula: C31H42N6O7 Molecular Weight: 610.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B275090
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    IUPAC Name
    2-[(3R,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazabicyclo[13.3.0]octadecan-3-yl]show more
    SMILES
    CC(C)CC1C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)C(C)C)CC(=O)O)CC3=CNC4=CC=CC=C43
    InChIKey
    VYCMAAOURFJIHD-PJNXIOHISA-N
    InChI
    1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/show more
    Synonyms
    2-((3R,6S,9R,12R,17aS)-9-((1H-indol-3-yl)methyl)-6-isobutyl-3-isopropyl-1,4,7,10,13-pentaoxohexadecahydro-1H-pyrrolo[...
  8. (R)-(-)-Ibuprofen
    CAS: 51146-57-7 Formula: C13H18O2 Molecular Weight: 206.28
    In Stock Item #: L126048
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    IUPAC Name
    (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid
    SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
    InChIKey
    HEFNNWSXXWATRW-SNVBAGLBSA-N
    InChI
    1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m1/s1
    Synonyms
    AC-32024 | (2R)-2-(4-isobutylphenyl)propanoic acid | HY-78131B | (R)-(-)-Ibuprofen | alphaR-Sethyl-4-(2-methylpropyl)...
  9. 1-Thio-β-D-glucose sodium salt
    CAS: 10593-29-0 PubChem CID: 11413308 Formula: C6H11NaO5S Molecular Weight: 218.2
    Out of Stock Item #: T165691
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    IUPAC Name
    sodium;(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate
    SMILES
    C(C1C(C(C(C(O1)[S-])O)O)O)O.[Na+]
    InChIKey
    VKPBZIVFRYLHPT-WNFIKIDCSA-M
    InChI
    1S/C6H12O5S.Na/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-10,12H,1H2;/q;+1/p-1/t2-,3-,4+,5-,6+;/m1./s1
    Synonyms
    sodium [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanide | BETA-D-THIOGLUCOSE SODIUM SALT | SCH...
  10. GSK3β inhibitor II, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 478482-75-6 Formula: C14H10IN3OS Molecular Weight: 395.22
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: G338641
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    IUPAC Name
    2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole
    SMILES
    C1=CC(=CC(=C1)I)CSC2=NN=C(O2)C3=CC=NC=C3
    InChIKey
    ZRHRPGSSSVYBRG-UHFFFAOYSA-N
    InChI
    1S/C14H10IN3OS/c15-12-3-1-2-10(8-12)9-20-14-18-17-13(19-14)11-4-6-16-7-5-11/h1-8H,9H2
    Synonyms
    2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole | 2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl)-1,3,4-oxa...
  11. GSK-3 Inhibitor XIII, Inhibitor of aurora kinase A;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase
    CAS: 404828-08-6 Formula: C18H19N5 Molecular Weight: 305.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: G338805
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    Synonyms
    (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
  12. Hexadecanedioic Acid
    CAS: 505-54-4 EC Number: 208-013-5 Formula: C16H30O4 Molecular Weight: 286.41
    In Stock Item #: H157143
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    IUPAC Name
    hexadecanedioic acid
    SMILES
    C(CCCCCCCC(=O)O)CCCCCCC(=O)O
    InChIKey
    QQHJDPROMQRDLA-UHFFFAOYSA-N
    InChI
    1S/C16H30O4/c17-15(18)13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(19)20/h1-14H2,(H,17,18)(H,19,20)
    Synonyms
    HY-W018161 | RF8 | SCHEMBL36069 | Thapsate | AS-11659 | Hexadecane-1,16-dioic acid | HEXADECANEDIOICACID | Thapsic ac...
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