2-Hydroxychalcone - Moligand™, 10 mM in DMSO , CAS No.644-78-0

CAS: 644-78-0 Cat. No.: H1495233 Fórmula: C₁₅H₁₂O₂ Peso molecular: 224.26 Beilstein Registry Number: 8(4)1388 Número CE: 211-422-1

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB.

Specifications

Especificações e pureza

Moligand™, 10 mM in DMSO

Condições de armazenamento de armazenamento

Protected from light,Argon charged,Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Nomes e identificadores

• SMILES isoméricas: C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2O
• Peso molecular: 224.26
• Beilstein: 8(4)1388
• Reaxy-Rn: 147424
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=147424&ln=

Propriedades químicas e físicas

• Ponto de fusão (°C): ca 154° dec.

Referências

1. Jianglin Zhang, Fan Yang, Xia Sun, Lingyu Gao, Jing Yan, Xiuxian Chen, Yuhua Gu, Shuaijie Song, Fuliang Hu, Xu'’ai Lin, Simon Duttwyler, Hao Cheng, Stijn van der Veen.  (2025)  2-Hydroxychalcone is a gonococcal-specific antimicrobial with activity against elongation factor Tu and butanediol dehydrogenase.  LIFE SCIENCES,      [PMID:41015385] [10.1016/j.lfs.2025.123994]

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 644-78-0, the molecular formula is C15H12O2, and the molecular weight is 224.26 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.