4-Hydroxy-TEMPO - ≥98% , CAS No.2226-96-2

CAS: 2226-96-2 Cat. No.: H104510 Fórmula: C9H18NO2 Peso molecular: 172.24 Beilstein Registry Number: 1422990 Número CE: 218-760-9
Disponível para encomenda
GRADE & PURITY ≥98%
Synonyms
4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical | 4-Hydroxy-TEMPO Free Radical | TEMPOL Free Radical
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
★
Size
USA
Alemanha (EU)*
Price
Qty
1g
H104510-1g
3 Em stock
—
9,90US$
25g
H104510-25g
8 Em stock
—
11,90US$
100g
H104510-100g
7 Em stock
—
28,90US$
250g
H104510-250g
3 Em stock
—
54,90US$
500g
H104510-500g
6 Em stock
—
99,90US$
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 98 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies.


product description:

4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic.

Specifications

Sinónimos
4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical | 4-Hydroxy-TEMPO Free Radical | TEMPOL Free Radical
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
Membrane permeable superoxide scavenger. SOD simulation. Reduce inflammation caused by superoxide anions and peroxynitrite. Reduce oxidative stress.
Condições de armazenamento de armazenamento
Store at 2-8°C,Argon charged
Enviado em
Wet ice
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
INHIBITOR
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%
Nomes e identificadores
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/508814175
SMILES isoméricas
CC1(CC(CC(N1[O])(C)C)O)C
WGK Alemanha
1
RTECS
TN8991000
Peso molecular
172.24
Beilstein
1422990
Reaxy-Rn
11328213

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Alvos associados (humanos)
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H1299 (3248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HUVEC (11049 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aorta (2975 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot NumberCertificate TypeDataItem
A1824032Certificate of AnalysisAug 18, 2025 H104510
L2502114Certificate of AnalysisMay 08, 2025 H104510
H2514504Certificate of AnalysisMay 08, 2025 H104510
H2514327Certificate of AnalysisMay 08, 2025 H104510
H2514505Certificate of AnalysisMay 08, 2025 H104510
J2619045Certificate of AnalysisMay 08, 2025 H104510
F2509481Certificate of AnalysisMay 08, 2025 H104510
F2509476Certificate of AnalysisMay 08, 2025 H104510
F2509475Certificate of AnalysisMay 08, 2025 H104510
F2509390Certificate of AnalysisMay 08, 2025 H104510
B2626115Certificate of AnalysisMay 08, 2025 H104510
B2528166Certificate of AnalysisDec 16, 2024 H104510
A2503352Certificate of AnalysisDec 16, 2024 H104510
A2503351Certificate of AnalysisDec 16, 2024 H104510
A2503348Certificate of AnalysisDec 16, 2024 H104510
L2411436Certificate of AnalysisJul 18, 2024 H104510
L2411444Certificate of AnalysisJul 13, 2024 H104510
L2411450Certificate of AnalysisJul 13, 2024 H104510
H2405238Certificate of AnalysisJul 09, 2024 H104510
H2405232Certificate of AnalysisJul 09, 2024 H104510
H2405231Certificate of AnalysisJul 09, 2024 H104510
I2205238Certificate of AnalysisAug 01, 2022 H104510
I2203235Certificate of AnalysisAug 01, 2022 H104510
I2203236Certificate of AnalysisAug 01, 2022 H104510
I2203237Certificate of AnalysisAug 01, 2022 H104510
I2203238Certificate of AnalysisAug 01, 2022 H104510
I2203239Certificate of AnalysisAug 01, 2022 H104510
I2308184Certificate of AnalysisAug 01, 2022 H104510
I2308185Certificate of AnalysisAug 01, 2022 H104510
C2418080Certificate of AnalysisAug 01, 2022 H104510
C2418077Certificate of AnalysisAug 01, 2022 H104510
A2410057Certificate of AnalysisAug 01, 2022 H104510
F2209157Certificate of AnalysisJul 28, 2021 H104510
Propriedades químicas e físicas
SolubilidadeEasily soluble in organic solvents such as ethanol and benzene, and easily soluble in water.
Sensibilidadelight sensitive & Moisture sensitive
Ponto de inflamação (°F)294.80℉
Ponto de inflamação (°C)146℃
Ponto de fusão (°C)69-71°C
Peso molecular172.240 g/mol
XLogP30.900
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass172.134 Da
Monoisotopic Mass172.134 Da
Topological Polar Surface Area24.500 Ų
Heavy Atom Count12
Formal Charge0
Complexity159.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs e artigos
Citations of This Product
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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