9-Phenanthrol - Moligand™, technical grade , Channel blocker of TRPM4, CAS No.484-17-3, Channel blocker of TRPM4

CAS: 484-17-3 Cat. No.: P136335 Fórmula: C₁₄H₁₀O Peso molecular: 194.23 Número CE: 207-602-4 PubChem CID: 10229

GRADE & PURITY Moligand™, Technical grade

Synonyms

HY-108457 | NSC50554 | NSC-50554 | UNII-9FYU45OV9H | DTXCID7027592 | DZKIUEHLEXLYKM-UHFFFAOYSA- | 4-06-00-04937 (Beilstein Handbook Reference) | Tox21_300618 | BRN 2047057 | GTPL4114 | SY113803 | Phenanthren-9-ol | SCHEMBL508755 | BDBM50526033 | CCRIS 184

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

HY-108457 | NSC50554 | NSC-50554 | UNII-9FYU45OV9H | DTXCID7027592 | DZKIUEHLEXLYKM-UHFFFAOYSA- | 4-06-00-04937 (Beilstein Handbook Reference) | Tox21_300618 | BRN 2047057 | GTPL4114 | SY113803 | Phenanthren-9-ol | SCHEMBL508755 | BDBM50526033 | CCRIS 184

Especificações e pureza

Moligand™, technical grade

Mecanismos bioquímicos e fisiológicos

Selective TRPM4 blocker (IC 50 = 20 μM). Modulates smooth muscle contraction. Reduces LPS-induced cell death. Promotes angiogenesis. Shows cardioprotective and anti-ischemic effects in vivo.

Condições de armazenamento de armazenamento

Room temperature

Enviado em

Normal

Grau

Grau técnico, Moligand™

Tipo de ação

CHANNEL BLOCKER

Mecanismo de ação

Channel blocker of TRPM4

Nota

Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nomes e identificadores

Pubchem Sid

504751916

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751916

Sorrisos canónicos

C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O

IUPAC Name

phenanthren-9-ol

InChIKey

DZKIUEHLEXLYKM-UHFFFAOYSA-N

INCHI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

SMILES isoméricas

C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O

WGK Alemanha

3

RTECS

SF8288000

PubChem CID

10229

Peso molecular

194.23

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Phenanthrenes and derivatives
      • Subclass Phenanthrols

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Phenanthrenes and derivatives
• Subclass: Phenanthrols
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenanthrols
• Alternative Parents: Naphthols and derivatives 1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Phenanthrol - 1-naphthol - 2-naphthol - Naphthalene - 1-hydroxy-2-unsubstituted benzenoid - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as phenanthrols. These are compounds containing a phenanthrene (or its hydrogenated derivative) to which a hydroxyl group is attached.
• External Descriptors: phenanthrol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (0 Activities)

Discover Target: TRPM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HL-60 (67320 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 194.230 g/mol
• XLogP3: 3.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 194.073 Da
• Monoisotopic Mass: 194.073 Da
• Topological Polar Surface Area: 20.200 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 225.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does technical grade mean?

technical grade indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 484-17-3, the molecular formula is C14H10O, and the molecular weight is 194.23 g/mol. InChIKey DZKIUEHLEXLYKM-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.