≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
AER-271 is an inhibitor of aquaporin-4.
In Vivo：Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA, rats treated with AER-271 did not develop significant neuronal death or neuroinflammation as compared to sham.
IC50& Target:Aquaporin-4 (AQP4)
| Pubchem Sid | 528763035 |
|---|---|
| Sorrisos canónicos | C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)OP(=O)(O)O |
| IUPAC Name | [2-[[3,5-bis(trifluoromethyl)phenyl]carbamoyl]-4-chlorophenyl] dihydrogen phosphate |
| InChIKey | WSHXPHFIHYXZKC-UHFFFAOYSA-N |
| INCHI | 1S/C15H9ClF6NO5P/c16-9-1-2-12(28-29(25,26)27)11(6-9)13(24)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6H,(H,23,24)(H2,25,26,27) |
| SMILES isoméricas | C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)OP(=O)(O)O |
| PubChem CID | 10412080 |
| Termos de entrada MeSH | 2-((3,5-Bis(trifluoromethyl) phenyl)carbamoyl)-4-chlorophenyl dihydrogen phosphate;AER-271 |
| Peso molecular | 463.65 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Anilides |
| Intermediate Tree Nodes | Aromatic anilides |
| Direct Parent | Benzanilides |
| Alternative Parents | Phenyl phosphates Trifluoromethylbenzenes 3-halobenzoic acids and derivatives Benzamides Phenoxy compounds Benzoyl derivatives Chlorobenzenes Aryl chlorides Secondary carboxylic acid amides Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives Alkyl fluorides Organonitrogen compounds Organooxygen compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzanilide - Phenyl phosphate - 3-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Trifluoromethylbenzene - Aryl phosphomonoester - Aryl phosphate - Benzamide - Benzoic acid or derivatives - Benzoyl - Phenoxy compound - Halobenzene - Chlorobenzene - Aryl chloride - Organic phosphoric acid derivative - Phosphoric acid ester - Aryl halide - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Alkyl fluoride - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Alkyl halide - Aromatic homomonocyclic compound |
| Descrição | This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Item |
|---|---|---|---|
 A2423107 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423111 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423112 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423120 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423121 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423122 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423123 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423124 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423135 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| A2423136 | Certificate of Analysis | Jan 13, 2024 | A649710 |
| Solubilidade | DMSO : 125 mg/mL (269.60 mM; Need ultrasonic) |
|---|---|
| Peso molecular | 463.650 g/mol |
| XLogP3 | 3.500 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 4 |
| Exact Mass | 462.981 Da |
| Monoisotopic Mass | 462.981 Da |
| Topological Polar Surface Area | 95.900 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 620.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
