Amoxicilina de sódio - ≥99% , CAS No.34642-77-8

CAS: 34642-77-8 Cat. No.: A129285 Fórmula: C₁₆H₁₈N₃O₅S.Na Peso molecular: 387.39 Número CE: 252-124-1

GRADE & PURITY ≥99%

Synonyms

Quimiopen | BYHDFCISJXIVBV-YWUHCJSESA-M | (2S-(2alpha,5alpha,6beta(S*)))-6-((Amino(4-hidroxifenil)acetil)amino)-3,3-dimetil-7-oxo-4-thia-1-azabicyclo(3.2.0)heptano-2-carboxílico sal monossódico | CHEBI:51255 | sódio (2S,5R,6R)-6-((R)-2-amino-2-(4-h

Storage

Armazenar a -20°C

Shipped In

Arca de gelo + almofadas de gelo

Visão geral

A amoxicilina de sódio é um antibiótico β-lactâmico de espetro moderado, bacteriolítico

Specifications

Sinónimos

Quimiopen | BYHDFCISJXIVBV-YWUHCJSESA-M | (2S-(2alpha,5alpha,6beta(S*)))-6-((Amino(4-hidroxifenil)acetil)amino)-3,3-dimetil-7-oxo-4-thia-1-azabicyclo(3.2.0)heptano-2-carboxílico sal monossódico | CHEBI:51255 | sódio (2S,5R,6R)-6-((R)-2-amino-2-(4-h

Especificações e pureza

≥99%

Mecanismos bioquímicos e fisiológicos

Agente antibiótico β-lactâmico de espetro moderado. Inibe a biossíntese da parede celular bacteriana ao impedir a reticulação do peptidoglicano. Apresenta efeitos bacteriocidas contra espécies gram-positivas e gram-negativas in vivo. Ativo por via oral.

Condições de armazenamento de armazenamento

Armazenar a -20°C

Enviado em

Arca de gelo + almofadas de gelo

Nota

Sempre que possível, deve preparar e utilizar as soluções no mesmo dia. No entanto, se precisar de preparar soluções de reserva com antecedência, recomendamos que guarde a solução como alíquotas em frascos hermeticamente fechados a -20°C. Em geral, estas podem ser utilizadas durante um mês. Antes de utilizar, e antes de abrir o frasco para injectáveis, recomendamos que deixe o seu produto equilibrar à temperatura ambiente durante pelo menos 1 hora. Precisa de mais conselhos sobre solubilidade, utilização e manuseamento? Para mais informações, visite a nossa página de perguntas frequentes (FAQ).

Pureza

≥99%

Nomes e identificadores

• Pubchem Sid: 528776337
• Sorrisos canónicos: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)[O-])C.[Na+]
• IUPAC Name: sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChIKey: BYHDFCISJXIVBV-YWUHCJSESA-M
• INCHI: 1S/C16H19N3O5S.Na/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
• SMILES isoméricas: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)[O-])C.[Na+]
• Peso molecular: 387.39
• Reaxy-Rn: 1184044
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1184044&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 N-acyl-alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: N-acyl-alpha amino acids and derivatives
• Alternative Parents: Penams Aralkylamines Phenoxides Thiazolidines Tertiary carboxylic acid amides Amino acids Azetidines Thiohemiaminal derivatives Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Carboximidic acids Carboxylic acids Dialkylthioethers Monocarboxylic acids and derivatives Organopnictogen compounds Hydrocarbon derivatives Monoalkylamines Carbonyl compounds Organic oxides Organic sodium salts Organic zwitterions
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-acyl-alpha amino acid or derivatives - Penam - Phenoxide - Aralkylamine - Monocyclic benzene moiety - Benzenoid - Beta-lactam - Tertiary carboxylic acid amide - Thiazolidine - Carboxamide group - Lactam - Azetidine - Amino acid - Azacycle - Organic alkali metal salt - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Thioether - Hemithioaminal - Dialkylthioether - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organonitrogen compound - Organic oxygen compound - Organic sodium salt - Organooxygen compound - Organopnictogen compound - Organic oxide - Primary amine - Organic salt - Organic nitrogen compound - Hydrocarbon derivative - Organic zwitterion - Amine - Carbonyl group - Primary aliphatic amine - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: DMSO 78 mg/mL Water 78 mg/mL Ethanol <1 mg/mL
• Sensibilidade: Hygroscopic
• Peso molecular: 387.400 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 387.086 Da
• Monoisotopic Mass: 387.086 Da
• Topological Polar Surface Area: 161.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 596.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referências

1. Wenying Zou, Junjun Wang, Siyi Yang, Yue Tang, Xiaojuan Niu, Yuangen Wu.  (2023)  Porous-nanozyme-based colorimetric sensor for rapid detection of kanamycin in foods under neutral condition.  JOURNAL OF FOOD SCIENCE,  88  (5): (2009-2022).  [PMID:37043597] [10.1111/1750-3841.16570]

2. Jing Zhao, Yuangen Wu, Han Tao, Huayun Chen, Wenping Yang, Shuyi Qiu.  (2017)  Colorimetric detection of streptomycin in milk based on peroxidase-mimicking catalytic activity of gold nanoparticles.  RSC Advances,  7  (61): (38471-38478).  [PMID:] [10.1039/C7RA06434A]