(+)-Biotin hydrazide - ≥98% , CAS No.66640-86-6

CAS: 66640-86-6 Cat. No.: B122221 Fórmula: C₁₀H₁₈N₄O₂S Peso molecular: 258.34 Beilstein Registry Number: 28347 Número CE: 613-970-0

GRAU & PUREZA ≥98%

Synonyms

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide | 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS-(3aalpha,4beta,6aalpha))- | Biotin-NHNH2 | AS-74083 | 1H-Thieno[3,4-d]imidazole-4-pent

Storage

Store at 2-8°C

Shipped In

Wet ice

Visão geral

Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties.Biotin hydrazide can be used to prepare biotin-conjugated alginate.It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.
Reagent for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone formation.

Especificações

Sinónimos

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide | 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS-(3aalpha,4beta,6aalpha))- | Biotin-NHNH2 | AS-74083 | 1H-Thieno[3,4-d]imidazole-4-pent

Especificações e pureza

≥98%

Condições de armazenamento de armazenamento

Store at 2-8°C

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

Pubchem Sid

504755733

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504755733

Sorrisos canónicos

C1C2C(C(S1)CCCCC(=O)NN)NC(=O)N2

IUPAC Name

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide

InChIKey

KOZWHQPRAOJMBN-ZKWXMUAHSA-N

INCHI

1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1

SMILES isoméricas

C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NN)NC(=O)N2

WGK Alemanha

3

Peso molecular

258.34

Beilstein

28347

Reaxy-Rn

260325

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=260325&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Biotin and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Biotin and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Biotin and derivatives
• Alternative Parents: Thienoimidazolidines Imidazolidinones Thiophenes Thiolanes Ureas Carboxylic acid hydrazides Dialkylthioethers Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Biotin_derivative - Thienoimidazolidine - Imidazolidinone - Imidazolidine - Thiolane - Thiophene - Carboxylic acid hydrazide - Carbonic acid derivative - Urea - Carboxylic acid derivative - Azacycle - Thioether - Dialkylthioether - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organic nitrogen compound - Carbonyl group - Aliphatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as biotin and derivatives. These are organic compounds containing a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Sensibilidade: Heat sensitive
• Ponto de fusão (°C): 233 °C
• Peso molecular: 258.339 g/mol
• XLogP3: -0.700
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 258.115 Da
• Monoisotopic Mass: 258.115 Da
• Topological Polar Surface Area: 122.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 313.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1