Butoconazole nitrate - 10mM in DMSO , Cytochrome P450 51 inhibitor, CAS No.64872-77-1, Cytochrome P450 51 inhibitor

CAS: 64872-77-1 Cat. No.: B408447 Fórmula: C₁₉H₁₇Cl₃N₂S·HNO₃ Peso molecular: 474.79 Número CE: 613-721-6 PubChem CID: 47471

GRADE & PURITY 10mM in DMSO

Synonyms

RS-35887 | 1-​[4-​(4-​chlorophenyl)​-​2-​[(2,​6-​dichlorophenyl)​thio]​butyl]​-​1H-​imidazole,nitrate (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Butoconazole nitrate Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL,
In vitro

In vivo

Cell Data

cell lines：NCI-H1703 cells

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinónimos

RS-35887 | 1-​[4-​(4-​chlorophenyl)​-​2-​[(2,​6-​dichlorophenyl)​thio]​butyl]​-​1H-​imidazole,nitrate (1:1)

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Mecanismo de ação

Cytochrome P450 51 inhibitor

Nomes e identificadores

• SMILES isoméricas: C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-]
• PubChem CID: 47471
• Peso molecular: 474.79

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro DMSO: 91 mg/mL (138.99 mM); Water: Insoluble; Ethanol: Insoluble
• Ponto de fusão (°C): 163 °C