C8-Alkyne-dU-CEP , CAS No.938186-76-6

CAS: 938186-76-6 Cat. No.: C487376 Fórmula: C₄₇H₅₅N₄O₈P Peso molecular: 834.94 PubChem CID: 99694933

Synonyms

C8-Alkyne dU phosphoramidite, 5-(Octa-1,7-diynyl)-3′-O-[(2-cyanoethoxy)(diisopropylamino)-phosphono)]-5′-O- (4,4′-dimethoxytrityl)-2′-deoxyuridine, 5-Octadiynyl-dU CEP

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Description

This functional phosphoramidite is used to introduce click handles univerally (5′ internal and 3′end) into oligonucleotides under standard conditions for solid phase synthesis. Afterwards the oligonucleotide (RNA, PNA, DNA) can be efficiently conjugated using a copper-catalyzed click reaction to azide-functionalized moieties such as fluorescent dye azides and azido amino acids

Specifications

Sinónimos

C8-Alkyne dU phosphoramidite, 5-(Octa-1,7-diynyl)-3′-O-[(2-cyanoethoxy)(diisopropylamino)-phosphono)]-5′-O- (4,4′-dimethoxytrityl)-2′-deoxyuridine, 5-Octadiynyl-dU CEP

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

Sorrisos canónicos

CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#CCCCCC#C

IUPAC Name

3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-octa-1,7-diynyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

MKSBKPPIZWOEHY-SSOUGYATSA-N

INCHI

1S/C47H55N4O8P/c1-8-9-10-11-12-14-18-36-32-50(46(53)49-45(36)52)44-31-42(59-60(57-30-17-29-48)51(34(2)3)35(4)5)43(58-44)33-56-47(37-19-15-13-16-20-37,38-21-25-40(54-6)26-22-38)39-23-27-41(55-7)28-24-39/h1,13,15-16,19-28,32,34-35,42-44H,9-12,17,30-31,33H2,2-7H3,(H,49,52,53)/t42-,43+,44+,60?/m0/s1

SMILES isoméricas

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#CCCCCC#C

PubChem CID

99694933

Peso molecular

834.94

Propriedades químicas e físicas

• Ponto de inflamação (°F): Not applicable
• Ponto de inflamação (°C): Not applicable