Corylifol A - 10mM in DMSO , CAS No.775351-88-7

CAS: 775351-88-7 Cat. No.: C655502 Fórmula: C₂₅H₂₆O₄ Peso molecular: 390.47 PubChem CID: 25056407

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC 50 of 0.81 μM.

In Vitro

Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC 50 value of 0.81±0.15 μM, also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. Corylifol A inhibits SARA PLpro in a dose-dependent manner with IC 50 s ranging between 4.2 and 38.4 μM. Corylifol A is found to be a naturally occurring potent inhibitor of hCE2, with low K i values ranging from 0.62 μM to 3.89 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:STAT3 0.81 μM (IC 50 )

Specifications

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC 50 of 0.81 μM.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

• SMILES isoméricas: CC(=CCC/C(=C/CC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)/C)C
• CAS alternativo: 775351-88-7
• PubChem CID: 25056407
• Termos de entrada MeSH: corylifol A
• Peso molecular: 390.47

Perguntas frequentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 775351-88-7, the molecular formula is C25H26O4, and the molecular weight is 390.47 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.