(+)-Dehydroabietylamine [Optical Resolving Agent] - ≥90%(GC) , CAS No.1446-61-3
Em stock
SKU
D154779
Pyruvate dehydrogenase kinase (PDK) inhibitor
Leelamine is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor with an IC50 value of 9.5 μM, showing a blood glucose lowering effect in the diabetic mouse. Leelamine is also a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine decreases mitotic activity, prostate-specific antigen expression and induces Apoptosis to cell death in cancer cells.
Mais informação
| CAS | 1446-61-3 |
|---|---|
| Sinónimos | EPA Pesticide Chemical Code 004206 | 13-Isopropylpodocarpa-8,11,13-trien-15-amine | Amine D | ((1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methanamine | Q15409408 | (+)-Dehydroabietylamine; >95% | Leelamine | W-10 |
| Especificações e pureza | ≥90%(GC) |
| Condições de armazenamento de armazenamento | Protected from light,Room temperature |
| Enviado em | Normal |
| Product Description | Leelamine is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor with an IC50 value of 9.5 μM, showing a blood glucose lowering effect in the diabetic mouse. Leelamine is also a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine decreases mitotic activity, prostate-specific antigen expression and induces Apoptosis to cell death in cancer cells. |
| Pubchem Sid | 488183548 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488183548 |
| Número de identificação | MFCD00213430 |
| Número CE | 215-899-7 |
| PubChem CID | 62034 |
| Fórmula molecular | C20H31N |
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